PET Geometric Calibration via Uniform Phantom Feedback

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Solution Overview

Problem

Conventional PET imaging systems face challenges in geometric calibration due to manufacturing tolerances and material differences, leading to image artifacts such as 'bands' and 'divots' that affect diagnostic accuracy.

Innovation Solution

An image-domain based iterative calibration method using a uniform phantom to generate reference images and determine geometric calibration coefficients, reducing image artifacts through feedback loops without requiring additional calibration equipment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a rotating pin source is used for geometric calibration, then measurement of coincidence pairs for every line of response is enabled, but detector dead time issues and count overload occur degrading calibration quality

Engineering Contradiction:
Improvegeometric calibration measurementVSAvoidcalibration data quality
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent extracts the essential calibration function from the rotating pin source method and implements it using a stationary uniform phantom. This eliminates the mechanical rotation component that causes dead time issues while preserving the ability to measure coincidence pairs for geometric calibration across all lines of response.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The uniform phantom serves as an intermediary object that enables geometric calibration without the drawbacks of a rotating pin source. It provides a stable, uniform distribution of coincidence events that allows measurement of all LORs without causing detector overload or dead time problems.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If the pin source rotates very close to detector faces to enable calibration, then complete LOR coverage is achieved, but detectors near the pin become overloaded with counts increasing dead time

Engineering Contradiction:
Improvegeometric calibration coverageVSAvoiddetector count overload
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent removes the rotating pin source that causes detector overload and replaces it with a uniform phantom. This extraction eliminates the localized high-count problem while maintaining the ability to calibrate all detector pairs through the uniform distribution of calibration events throughout the phantom volume.

Inventive Principle:
Principle #2Taking out (Extraction)

3Measurement precision

If conventional calibration methods are used, then geometric corrections can be obtained, but image artifacts such as bands and divots appear in reconstructed images

Engineering Contradiction:
Improvegeometric correction coefficientsVSAvoidimage artifacts
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

The patent converts the uniform phantom into a beneficial calibration tool that eliminates the harmful image artifacts produced by conventional methods. By using the uniform phantom's homogeneous radioactivity distribution, the method produces accurate geometric corrections without the bands and divots that plague conventional calibration approaches.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Data Source

PatentUS8452064B2Apparatus and methods for geometric calibration of positron emission tomography systems
Publication Date: 2013.05.28 GE PRECISION HEALTHCARE LLC
  • US8452064B2 patent drawing
  • US8452064B2 patent drawing
  • US8452064B2 patent drawing

AI summary

Apparatus and methods for geometric calibration of positron emission tomography (PET) systems are provided. One method includes obtaining scan data for a uniform phantom and generating reference images based on the scan data for the uniform phantom. The method further includes reconstructing images of the uniform phantom using a PET imaging system and determining a geometric calibration for the PET imaging system based on a comparison of the reconstructed images and the reference images.