Tomographic Imaging Apparatus with Integrated PET and CT Detectors

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Solution Overview

Problem

Current PET-guided radiation therapy systems face limitations due to low spatial resolution and high scattering artifacts in CT imaging, which restricts real-time imaging and precise therapy, especially with the need for separate scanning planes for PET and CT, leading to inaccuracies and increased radiation dose.

Innovation Solution

The proposed tomographic imaging and image-guided radiation therapy apparatus includes a CT detector positioned between PET detectors, equipped with a de-scattering unit, and a KV ray source to improve spatial resolution and detection sensitivity, allowing for simultaneous KV CT and PET imaging, and guiding radiation therapy with reduced scattering artifacts.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a separate kilovolt CT subsystem is used for CT imaging, then the spatial resolution and contrast are improved, but the device complexity and restrictions on simultaneous imaging are increased

Engineering Contradiction:
Improvespatial resolutionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines the kilovolt CT subsystem with the PET detector assembly by integrating the KV ray source and CT detectors into the existing PET detector structure. The CT detectors are positioned within the PET detector housing, allowing both PET and CT imaging functions to share the same physical platform and scanning mechanics, thereby reducing overall device complexity while maintaining high spatial resolution CT imaging capabilities

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The PET detector assembly is designed to perform multiple functions: it serves as both the PET detection system and the CT imaging system. The same mechanical structure, rotation mechanism, and positioning system are used for both PET and CT acquisitions, eliminating the need for separate dedicated CT subsystem components and reducing device complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If PET and CT imaging are performed on separate scanning planes, then the PET imaging performance is maintained, but the image registration accuracy and real-time imaging capability are reduced

Engineering Contradiction:
ImprovePET imaging performanceVSAvoidimage registration accuracy
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The patent merges the PET and CT scanning planes into a single coplanar configuration. The KV ray source and CT detectors are positioned within the PET detector assembly such that both imaging modalities acquire data from the same scanning plane and angular positions. This coplanar arrangement ensures that PET and CT images are naturally registered without requiring complex post-processing alignment, while the energy discrimination capabilities of the detectors maintain PET imaging performance

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent employs asymmetric detector positioning where CT detectors are strategically placed within the PET detector assembly at specific angular positions and distances from the KV ray source. This asymmetric configuration optimizes both CT image quality and PET detection efficiency within the coplanar geometry, allowing simultaneous imaging without compromising either modality's performance

Inventive Principle:
Principle #4Asymmetry

3Ease of operation

If a megavolt CT is used for therapy guidance, then the convenience for image registration and therapy optimization is improved, but the imaging quality and patient radiation dose are worsened

Engineering Contradiction:
Improveimage registration convenienceVSAvoidimaging quality
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent changes the energy parameter of the X-ray source from megavolt to kilovolt range. By using a kilovolt X-ray source instead of megavolt, the system achieves significantly improved image quality with higher contrast and better spatial resolution. The kilovolt energy level optimizes the balance between image quality and radiation dose, providing diagnostic-quality CT images for accurate therapy guidance without the excessive dose associated with megavolt CT

Inventive Principle:
Principle #35Parameter changes

4Measurement precision

If a kilovolt CT is used for imaging, then the imaging quality and radiation dose are improved, but the ability to perform simultaneous imaging with PET is restricted

Engineering Contradiction:
Improveimaging qualityVSAvoidsimultaneous imaging capability
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent enables continuous simultaneous operation of both PET and CT imaging functions. The integrated detector assembly allows both modalities to acquire data continuously during the same scanning motion without requiring sequential operation. The system can perform PET and CT acquisitions simultaneously or in rapid succession, eliminating idle time and maximizing productivity while maintaining high imaging quality

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The patent employs periodic switching between PET and CT detection modes within the integrated detector assembly. The detectors can rapidly alternate between optimizing for PET coincidence detection and CT attenuation measurement, or simultaneously process both signal types through energy discrimination. This periodic or simultaneous detection strategy enables both high-quality imaging and continuous scanning capability

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This configuration enhances the spatial resolution and detection sensitivity of CT imaging, reduces scattering artifacts, and maintains the performance of PET imaging, enabling more accurate and efficient radiation therapy with reduced radiation dose.

Implementation Method 1

at least one KV ray source for providing KV ray for medical diagnosis

Methodology Applied
Scientific EffectX-ray generation: X-Ray

Implementation Method 2

In the PET imaging, gamma photons produced by positron annihilation have a potential to directly reflect real-time location information of the tumor in the body of the patient

Methodology Applied
Scientific EffectPositron annihilation:

Implementation Method 3

the second PET detector and the CT detector are configured to receive the KV ray to perform a KV CT imaging

Methodology Applied
Scientific EffectX-ray detection: X-Ray

Data Source

PatentUS11179579B2Tomographic imaging and image-guided radiation therapy apparatus
Publication Date: 2021.11.23 TSINGHUA UNIVERSITY
  • US11179579B2 patent drawing
  • US11179579B2 patent drawing
  • US11179579B2 patent drawing

AI summary

An image-guided radiation therapy apparatus comprises: a high-energy ray source configured for radiation therapy of an object; and a KV ray source, a first and second PET detectors, and a CT detector for KV CT and PET imaging for guiding the radiation therapy. The KV ray source is placed on, or at an inner or outer side of the first PET detector; the second PET detector and the CT detector are configured to receive the KV ray to perform KV CT imaging; the PET detectors are further configured to receive gamma ray emitted by the object to perform PET imaging.