PET Parameter Image Enhancement via Iterative Deep Learning

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Solution Overview

Problem

Existing neural network models for enhancing PET parameter images require high-quality images for training, which are difficult to obtain due to longer scanning times or higher tracer doses, not meeting clinical image acquisition requirements.

Innovation Solution

A method that determines an original PET parameter image from a dynamic PET image set, obtains an input image using a preset mapping list, and adjusts the model parameters of an image enhancement model based on the original and predicted PET parameter images until a preset number of iterations is met, using the predicted image as a target image.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a filtering algorithm is used to improve image quality of PET parameter images, then noise is reduced, but spatial resolution is reduced and image details are damaged

Engineering Contradiction:
Improveimage qualityVSAvoidspatial resolution
Core Design Contradiction:
Measurement precisionVSManufacturing precision

Solution Approach 1:

The patent replaces traditional mechanical filtering algorithms with a deep learning-based image enhancement model. The model uses convolutional neural networks to learn the mapping between low-quality and high-quality images, substituting the mechanical filtering process with an intelligent system that can preserve spatial resolution while reducing noise through learned patterns rather than fixed mathematical operations.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the fundamental parameters of the image enhancement process by using a trained neural network model with optimized weights and biases. Instead of applying fixed filtering parameters, the system uses learned parameters from training data to dynamically adjust the enhancement process, allowing simultaneous noise reduction and detail preservation through adaptive parameter selection.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If a neural network model is used to enhance PET parameter images, then image quality is improved, but high-quality training labels are required which need longer scanning time or higher tracer injection doses

Engineering Contradiction:
Improveimage qualityVSAvoidscanning time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent uses synthetic data generation to create artificial high-quality PET parameter images that serve as training labels. Instead of requiring actual clinical high-quality scans, the system generates synthetic training data through simulation and computational methods, copying the essential characteristics needed for training without the time and resource costs of acquiring real high-quality medical images.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent replaces expensive, time-consuming real high-quality medical images with computationally generated synthetic images. These synthetic training labels are inexpensive to produce and can be generated rapidly without requiring actual patient scanning time or additional tracer doses, effectively substituting valuable clinical resources with affordable computational alternatives.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Measurement precision

If a neural network model is used to enhance PET parameter images, then image quality is improved, but higher tracer injection doses are required for training

Engineering Contradiction:
Improveimage qualityVSAvoidtracer injection dose
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The patent generates synthetic training data that replicates the essential features of high-quality PET images without requiring actual high-dose tracer injections. The synthetic data copying approach creates virtual training examples that preserve the statistical and structural properties needed for model training while eliminating the need for additional radioactive tracer administration to patients.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent substitutes expensive radioactive tracer materials with computationally generated synthetic data. The synthetic training labels serve as disposable, inexpensive alternatives to real high-dose images, eliminating the need to consume additional tracer substances while providing sufficient training material for the neural network model.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Data Source

PatentUS20250148574A1Method and apparatus for enhancing pet parameter image, device, and storage medium
Publication Date: 2025.05.08 SHENZHEN INST OF ADVANCED TECH
  • US20250148574A1 patent drawing
  • US20250148574A1 patent drawing
  • US20250148574A1 patent drawing

AI summary

The present disclosure discloses a method and apparatus for enhancing a PET parameter image, a device, and a storage medium. The method includes: obtaining, based on a preset mapping list, an input image corresponding to an original PET parameter image determined based on a dynamic PET image set; and inputting the input image into an image enhancement model, adjusting a model parameter of the image enhancement model based on the original PET parameter image and an output predicted PET parameter image until a preset number of iterations is met, and using the predicted PET parameter image as a target PET parameter image corresponding to the original PET parameter image; wherein the input image is a noise image, a dynamic PET image corresponding to a preset acquisition time range in the dynamic PET image set or a dynamic SUV image corresponding to the dynamic PET image.