Neural Network PET Image Transformation for Cost Reduction

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Solution Overview

Problem

High-end PET/CT systems face challenges in cost reduction while maintaining performance, as less expensive crystals compromise TOF resolution, and conventional software solutions are insufficient to bridge the gap between system performance and customer needs in low-end systems.

Innovation Solution

A deep learning approach that utilizes a neural network to transform images from low-end PET/CT systems into images comparable to those from high-end systems by training on datasets from both systems, minimizing difference metrics and improving image quality without hardware modifications.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If less expensive crystals are used in PET/CT systems, then manufacturing cost is reduced, but TOF resolution deteriorates

Engineering Contradiction:
Improvemanufacturing costVSAvoidTOF resolution
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

The patent creates a virtual copy of high-end system images through neural network transformation. The deep learning model learns the mapping between low-end and high-end system images, generating synthetic images that replicate the quality characteristics of expensive systems without requiring the actual expensive hardware components

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent replaces the physical hardware improvement path (upgrading crystals) with a software-based neural network system. Instead of improving the physical detection mechanism, the invention uses deep learning algorithms to post-process and transform images, substituting computational processing for mechanical/hardware enhancement

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If conventional reconstruction algorithms are used to improve low-end system performance, then image quality is partially improved, but the gap between system performance and customer needs remains insufficient

Engineering Contradiction:
Improveimage qualityVSAvoidsoftware complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent fundamentally changes the approach parameter from traditional iterative reconstruction algorithms to a deep learning-based transformation model. This parameter change enables the system to achieve superior image quality improvement by learning complex non-linear mappings between low-end and high-end system images, rather than relying on conventional linear or iterative methods

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If deep learning transformation is applied to low-end system images, then image quality comparable to high-end systems is achieved, but computational processing time increases

Engineering Contradiction:
Improveimage qualityVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent performs preliminary training of the neural network model using paired datasets from low-end and high-end systems before actual clinical use. This preliminary action creates a pre-trained transformation model that can be rapidly applied to patient images, separating the computationally intensive learning phase from the clinical application phase

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentEP3700425B1Positron emission tomography (PET) system design optimization using deep imaging
Publication Date: 2023.12.06 KONINKLIJKE PHILIPS NV
  • EP3700425B1 patent drawingFigure 1
  • EP3700425B1 patent drawingFigure 2

AI summary

An imaging method (100) includes: acquiring first training images of one or more imaging subjects using a first image acquisition device (12); acquiring second training images of the same one or more imaging subjects as the first training images using a second image acquisition device (14) of the same imaging modality as the first imaging device; and training a neural network (NN) (16) to transform the first training images into transformed first training images having a minimized value of a difference metric comparing the transformed first training images and the second training images.