Automatic PET Lesion Segmentation Algorithm Selection

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Solution Overview

Problem

There is no single universally effective algorithm for segmenting lesions in PET images, requiring manual selection and tuning based on specific conditions, which is time-consuming and inefficient, especially when comparing image datasets over time.

Innovation Solution

A method and system for automatically selecting a segmentation algorithm by defining a seed point and bounding box within a lesion, determining parameters, and choosing an appropriate algorithm from a list based on these parameters, allowing for consistent segmentation across similar anatomy datasets.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual selection and fine-tuning of segmentation algorithms is performed, then segmentation quality can be optimized for specific image conditions, but time consumption and operational complexity increase significantly

Engineering Contradiction:
Improvesegmentation qualityVSAvoidtime consumption
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system automatically selects and applies the most appropriate segmentation algorithm by analyzing image characteristics such as noise levels, SUV distribution, and artifact presence. This self-service mechanism eliminates the need for manual algorithm selection and fine-tuning, thereby reducing time consumption while maintaining optimized segmentation quality for each specific image condition

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system dynamically changes segmentation parameters and algorithm selection based on detected image characteristics. By automatically adjusting parameters such as noise thresholds, SUV cutoff values, and algorithm choice according to the specific image conditions, the system achieves optimized segmentation quality without requiring manual intervention for each case

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If manual selection and fine-tuning of segmentation algorithms is performed, then segmentation accuracy can be improved, but operational complexity and expertise requirements increase

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidoperational complexity
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system performs automatic algorithm selection and parameter optimization without requiring user expertise in segmentation methodologies. The automated analysis of image characteristics and subsequent algorithm selection simplifies the operational process, making it accessible to users without specialized knowledge while maintaining high segmentation accuracy

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system introduces an automated intermediary process that bridges the gap between raw image data and accurate segmentation results. This intermediary automatically analyzes image characteristics, selects appropriate algorithms, and fine-tunes parameters, thereby eliminating the need for users to directly engage in complex algorithm selection while ensuring accurate segmentation outcomes

Inventive Principle:
Principle #24Intermediary (Mediator)

3Ease of operation

If a single segmentation algorithm is used for all image datasets, then operational simplicity is maintained, but segmentation quality varies across different lesion types and image conditions

Engineering Contradiction:
Improveoperational simplicityVSAvoidsegmentation quality
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The system automatically changes segmentation parameters and algorithm selection based on detected image characteristics such as noise levels, SUV distribution patterns, and artifact presence. This dynamic parameter adjustment allows the system to maintain operational simplicity while adapting to different lesion types and image conditions, thereby preserving segmentation quality across diverse scenarios

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system transitions from a static single-algorithm approach to a dynamic multi-algorithm selection process. By automatically analyzing image characteristics and selecting the most appropriate algorithm for each specific case, the system maintains operational simplicity for the user while achieving optimized segmentation quality adapted to each unique image condition

Inventive Principle:
Principle #15Dynamics

4Productivity

If segmentation algorithms are not reselected for subsequent image datasets, then workflow efficiency is maintained, but segmentation accuracy deteriorates when image characteristics change over time

Engineering Contradiction:
Improveworkflow efficiencyVSAvoidsegmentation accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system performs preliminary automatic analysis of image characteristics and pre-selects the most appropriate segmentation algorithm before actual segmentation is executed. This preliminary action ensures that when subsequent image datasets are processed, the correct algorithm is already selected and ready to apply, maintaining both workflow efficiency and segmentation accuracy without requiring manual reselection

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system automatically changes segmentation parameters and algorithm selection for each new image dataset based on its specific characteristics. This automated parameter adaptation ensures that segmentation accuracy is maintained across time-series images with varying characteristics, while the automated process preserves workflow efficiency by eliminating manual reselection steps

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS7953265B2Method and system for automatic algorithm selection for segmenting lesions on pet images
Publication Date: 2011.05.31 GE PRECISION HEALTHCARE LLC
  • US7953265B2 patent drawing
  • US7953265B2 patent drawing
  • US7953265B2 patent drawing

AI summary

A method and system is provided for automatically processing a volumetric diagnostic image dataset. A first seed point is defined within a lesion. The lesion is within a first image dataset representative of a subject. A first boundary is defined in three dimensions within the first image dataset and the first seed point and the lesion are within the first boundary. At least one parameter is determined based on the first image dataset. A first segmentation algorithm is selected from a plurality of segmentation algorithms based on the at least one parameter, and the lesion is segmented using the first segmentation algorithm.