PET Imaging List-Mode Data Synchronization via Software Clock

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Solution Overview

Problem

Current PET imaging systems face challenges in synchronizing list-mode data of single events due to limitations in clock synchronization methods, which affect time resolution and system flexibility, maintainability, and scalability.

Innovation Solution

A method and system for synchronizing list-mode data of single events in PET imaging using local reference clock sources without hardware synchronization signals, involving frequency difference compensation, probability density calculation, and iterative synchronization corrections to accurately synchronize data and extract coincidence events.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a backplane with clock distribution network is used for synchronization, then time resolution is improved, but system flexibility and scalability are worsened

Engineering Contradiction:
Improvetime resolutionVSAvoidsystem flexibility
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

The system divides the synchronization function into two parts: a master data acquisition board that generates the reference clock signal, and slave data acquisition boards that use software-based time synchronization. This segmentation eliminates the need for a physical backplane clock distribution network while maintaining synchronization precision, thereby improving system flexibility and scalability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent replaces the mechanical/hardware-based clock distribution network on the backplane with a software-based time synchronization mechanism. The master board sends time synchronization signals through standard communication interfaces, and slave boards use software algorithms to achieve precise time alignment, substituting physical connectivity with software-controlled timing.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If cables are used to transfer reference clock signal, then synchronization is achieved, but signal quality deteriorates due to delay, decay and noise

Engineering Contradiction:
Improvesynchronization capabilityVSAvoidsignal quality
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The patent introduces a software-based time synchronization protocol as an intermediary between the master and slave data acquisition boards. Instead of directly transmitting the reference clock signal through cables (which causes delay, decay, and noise), the system transmits timing information through software layers that can compensate for transmission errors and maintain signal integrity.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The slave data acquisition boards create local copies of the reference clock signal using their own local clock sources, synchronized to the master board's timing. This copying approach allows each slave board to generate its own clean, noise-free clock signal while maintaining synchronization with the master, avoiding the degradation that occurs when the master's clock signal is transmitted through cables.

Inventive Principle:
Principle #26Copying

3Reliability

If hardware coincidence circuit is used, then coincidence detection is achieved, but system maintainability is worsened

Engineering Contradiction:
Improvecoincidence detection capabilityVSAvoidsystem maintainability
Core Design Contradiction:
ReliabilityVSEase of repair

Solution Approach 1:

The patent replaces hardware coincidence circuits with software-based coincidence detection algorithms. The data acquisition boards collect timing data from multiple detectors, and the system performs coincidence detection through software processing. This substitution makes the system more maintainable because software can be updated, debugged, and modified without replacing physical hardware components, while maintaining the reliability of coincidence detection.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS10930031B2Synchronization method and system for single event list type data in PET imaging
Publication Date: 2021.02.23 RAYCAN TECH CO LTD SU ZHOU
  • US10930031B2 patent drawing
  • US10930031B2 patent drawing
  • US10930031B2 patent drawing

AI summary

A method for synchronizing list-mode data of single events in a PET imaging includes: acquiring list-mode data of single events of each independent detector module, calculating a probability density of time intervals between occurrences of single events in detector module and setting initial parameters, determining detection starting time difference of each detector module with iterative peak searching and graded time window, and performing synchronization correction and coincidence discrimination on the single event data in each detector module based on the detection starting time difference. A system for synchronizing list-mode data of single events in a PET imaging includes: a data acquisition and frequency difference compensation module, an initial parameter setting module, a coarse time scale coincidence module, a fine time scale coincidence module and a data synchronization correction and coincidence discrimination module.