Maize Inbred PH46P6 CMS Breeding Acceleration

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Solution Overview

Problem

The development of new maize varieties and hybrids is a time-consuming process, taking six to twelve years from the first cross to delivering finished seed to farmers, and existing technologies face challenges in creating stable, high-yielding varieties with desirable traits such as disease resistance, drought tolerance, and improved agronomic characteristics.

Innovation Solution

A novel maize variety, PH46P6, is developed through careful breeding and selection, incorporating traits like male sterility, disease resistance, and drought tolerance, achieved through backcross conversion, genetic manipulation, and transformation, allowing for the creation of hybrid seeds with enhanced agronomic traits.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional breeding processes are used to develop new maize varieties, then stable and high-yielding varieties with desirable traits can be achieved, but the process takes six to twelve years which is time-consuming

Engineering Contradiction:
Improvestability of maize varietyVSAvoidbreeding development time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent employs preliminary action by using male sterile lines and cytoplasmic male sterility (CMS) systems to prevent self-pollination before it can occur. This eliminates the need for manual detasseling and ensures that only controlled cross-pollination occurs, streamlining the breeding process while maintaining variety stability and reducing development time.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses cytoplasmic male sterility (CMS) as an intermediary mechanism to control pollination. The CMS trait acts as a mediator that prevents self-fertilization and ensures outcrossing, allowing breeders to efficiently develop hybrid varieties with desirable traits without the time-consuming process of traditional manual emasculation and pollination control.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If manual detasseling is performed to prevent self-pollination, then hybrid seed production can be achieved, but the process becomes labor-intensive and costly

Engineering Contradiction:
Improvehybrid seed productionVSAvoidbreeding process complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent implements self-service by utilizing cytoplasmic male sterility (CMS) in the female parent line, which automatically prevents self-pollination without requiring manual intervention. The plant itself serves the function of preventing self-fertilization through its sterile cytoplasm, eliminating the need for labor-intensive detasseling operations and reducing breeding process complexity.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The CMS trait serves as an intermediary that automates the pollination control function. Instead of requiring manual detasseling, the cytoplasmic sterility acts as a biological mediator that naturally prevents self-pollination, simplifying the hybrid seed production process while maintaining ease of operation.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Productivity

If inbred lines are used as parents, then hybrid vigor can be achieved, but the inbred lines themselves have reduced vigor due to homozygosity

Engineering Contradiction:
Improvehybrid yieldVSAvoidparental line vigor
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent applies dynamics by maintaining the inbred parental lines in a dormant or non-expressing state where their homozygous nature does not manifest as vigor reduction. When the hybrids are produced through controlled cross-pollination using CMS, the heterosis or hybrid vigor is expressed in the F1 generation, achieving high productivity while the parental inbreds can be maintained without showing vigor deficits.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent segments the genetic material into distinct inbred parental lines with specific homozygous traits. By maintaining these lines separately and using CMS to ensure controlled cross-pollination, the patent allows each parental line to contribute specific desirable traits to the hybrid without the need for the parental lines to exhibit vigor themselves, thus achieving high hybrid productivity while managing parental line characteristics.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS10980200B1Maize inbred PH46P6
Publication Date: 2021.04.20 PIONEER HI BREED INTERNATIONAL INC

AI summary

A novel maize variety designated PH46P6 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH46P6 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH46P6 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH46P6 or a locus conversion of PH46P6 with another maize variety.