Pharmaceutical Powder Filler with Static Reduction and Draft Shields

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Solution Overview

Problem

Existing filling systems struggle with high precision and accuracy when dispensing small quantities of pure API pharmaceuticals into containers, often due to electrostatic interference and powder particulate interactions, which can lead to inaccuracy and equipment inefficiency.

Innovation Solution

A filling system equipped with a filler having a powder filler head, a weight sensor, static reduction devices, and draft shields to minimize static and dust, ensuring accurate dispensing of powdered pharmaceuticals by using gravimetric measurement and dust extraction techniques.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional filling systems are used to dispense small quantities of powdered pharmaceuticals, then the filling process can be completed, but high precision and accuracy cannot be achieved due to electrostatic interference and powder particulate interactions

Engineering Contradiction:
Improvefilling accuracyVSAvoidelectrostatic interference
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

A conductive material is introduced as an intermediary between the powdered pharmaceutical and the filling system components. This conductive material serves as a mediator that dissipates electrostatic charges, preventing electrostatic interference from affecting the gravimetric measurement and dispensing accuracy. The conductive material creates a controlled electrical pathway that neutralizes the harmful electrostatic effects without interfering with the pharmaceutical product itself.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If conventional filling systems operate without additional protective measures, then the equipment structure remains simple, but dust from powder particulate interactions reduces filling accuracy and equipment efficiency

Engineering Contradiction:
Improvefilling accuracyVSAvoidpowder dust
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

Dust extraction technology is integrated into the filling system to remove powder dust particles from the filling environment. The extraction system actively captures and removes dust generated during powder handling and dispensing, preventing these particles from interfering with the gravimetric measurement process. This extraction mechanism separates the harmful dust particles from the controlled filling zone, maintaining measurement precision while allowing continuous operation.

Inventive Principle:
Principle #2Taking out (Extraction)

3Manufacturing precision

If gravimetric measurement is used to achieve high filling precision, then accurate dispensing can be achieved, but the system complexity increases due to the need for additional measurement and control components

Engineering Contradiction:
Improvedispensing accuracyVSAvoidsystem complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The filling system merges the gravimetric measurement function with the dispensing mechanism into an integrated unit. The load cell measurement system is combined with the powder dispensing components, allowing real-time weight monitoring and automatic control of the dispensing process. This integration enables high dispensing accuracy while minimizing system complexity by consolidating measurement and actuation functions into a unified control architecture.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system achieves precise and efficient filling of pure API pharmaceuticals by reducing static interference and dust, enabling consistent and accurate dispensing of small quantities within tight tolerances, enhancing both accuracy and equipment performance.

Implementation Method 1

a weight sensor positioned below the first powder filler head

Methodology Applied
Scientific EffectGravimetric measurement: Gravitation

Implementation Method 2

one or more static reduction devices arranged to reduce static generated during a filling process

Methodology Applied
Scientific EffectStatic electricity reduction: Electrostatics

Data Source

PatentEP3484772B1Apparatus and method for filling bulk materials into a container
Publication Date: 2023.12.20 AZURITY PHARMA INC
  • EP3484772B1 patent drawingFigure 1
  • EP3484772B1 patent drawingFigure 2
  • EP3484772B1 patent drawingFigure 3

AI summary

A system and method for dispensing a powdered pharmaceutical into a bottle is disclosed. The system includes a filler having a powder filler head and respective weight sensor, two or more draft shields, and one or more static reduction devices. In some embodiments, the system also includes one or more dust extractors. In some embodiments, the static reduction device is an active static reduction device, such as one or more static bars. The two or more draft shields may include an inner draft shield to reduce small pressure and/or airflow changes and an outer draft to reduce large pressure and/or airflow changes.