Pharmaceutical Compounding Workflow With Scale-Triggered Image Verification

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current systems for preparing pharmaceutical compounds lack automation in image capture during preparation, leading to potential errors in verification by pharmacists, and do not combine image and gravimetric verification methods to ensure accuracy.

Innovation Solution

A system that automatically triggers image capture using a scale's weight detection signals, displaying both image and gravimetric data to pharmacists for verification, allowing for step-by-step instruction and tolerance-based verification processes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual image capture is used during drug preparation, then the technician can document preparation steps, but errors may occur that prevent proper verification by the pharmacist

Engineering Contradiction:
Improveverification accuracyVSAvoidoperation complexity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The system performs self-service by automatically triggering image capture based on weight change detection from the scale, eliminating the need for technician intervention. The scale detects when a component is placed on it and automatically initiates image capture, ensuring consistent documentation without manual errors.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system uses feedback from the scale's weight detection to trigger the next action (image capture). The scale continuously monitors weight changes and provides feedback signals to the processor, which then activates the image capture device when predetermined weight thresholds are met, creating a closed-loop verification system.

Inventive Principle:
Principle #23Feedback

2Reliability

If only image verification is used for drug preparation, then the system is simpler, but it lacks gravimetric verification to ensure proper drug concentration

Engineering Contradiction:
Improvedrug concentration accuracyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system merges image verification and gravimetric verification into a single integrated workflow. The scale and image capture device work together, with the scale providing weight-based verification and the image capture providing visual documentation, both required for complete verification by the pharmacist.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The scale serves multiple functions: it monitors weight changes during preparation, triggers image capture events, and provides gravimetric verification data. This multi-functionality reduces the need for separate dedicated devices while maintaining comprehensive verification capabilities.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Extent of automation

If the technician must actively trigger image capture, then the system requires less automation, but errors occur that prevent proper verification

Engineering Contradiction:
Improveautomation levelVSAvoidverification data completeness
Core Design Contradiction:
Extent of automationVSLoss of information

Solution Approach 1:

The system performs preliminary action by pre-configuring weight thresholds and capture criteria before the preparation process begins. The scale is programmed with expected weight ranges for each preparation step, and automatically captures images when these predetermined conditions are met, ensuring no verification data is missed.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Ensures accurate and reliable preparation of pharmaceutical compounds by automating image capture and combining visual and weight verification, reducing human error and enhancing pharmacist review capabilities.

Implementation Method 1

a scale operatively connected to the at least one processor... configured to transmit a signal to the at least one processor indicating that a weight detected thereby has changed

Methodology Applied
Scientific EffectGravimetric measurement:

Implementation Method 2

an image capture device operatively connected to the at least one processor and the scale and positioned to capture an image of at least one of a component used in preparing the pharmaceutical compound and the pharmaceutical compound

Methodology Applied
Scientific EffectImage capture:

Data Source

PatentUS11763448B2System and method for preparing a pharmaceutical compound
Publication Date: 2023.09.19 BECTON DICKINSON & CO
  • US11763448B2 patent drawing
  • US11763448B2 patent drawing
  • US11763448B2 patent drawing

AI summary

A system for preparing a pharmaceutical compound comprises: a computing device comprising a user interface providing an operator with instructions for preparing the pharmaceutical compound and at least one processor operatively connected to the user interface; a scale operatively connected to the at least one processor; and an image capture device operatively connected to the at least one processor and the scale and positioned to capture an image of at least one of a component used in preparing the pharmaceutical compound and the pharmaceutical compound.