Periodic Phase-Dependent Guide Wire Tracking in Angiography
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Solution Overview
Problem
Current methods for locating guide wires or vessels during coronary artery interventions, such as fluoroscopy, face challenges due to low image contrast and difficulty in distinguishing soft tissues, especially under fluoroscopy where vessels are hard to visualize without contrast agents, and are exacerbated by cardiac and breathing motions.
Innovation Solution
A periodic time-varying model of the guide wire or vessel is created using high-contrast CINE acquisition data, employing multivariate curve regression to track the device's motion, which is then used to locate and enhance the visibility of the guide wire or vessel in fluoroscopy images.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Speed
If fluoroscopy is used for real-time monitoring during intervention, then radiation dose is reduced and imaging speed is improved, but image contrast deteriorates and vessel visibility worsens
Solution Approach 1:
The system performs preliminary action by acquiring high-contrast CINE images before the intervention procedure to establish a baseline model of the vessel and guide wire positions. This preliminary modeling allows the system to predict and compensate for motion effects during the actual fluoroscopy-guided intervention, resolving the contradiction between rapid imaging and clear visualization.
Solution Approach 2:
The patent introduces an intermediary computational model that mediates between the low-contrast fluoroscopy images and the high-contrast CINE reference data. This model, built from phase-dependent motion analysis, acts as a bridge to enhance fluoroscopy image quality without requiring actual high-contrast imaging during the intervention, thus maintaining both speed and visibility.
2Measurement precision
If CINE acquisition with contrast medium is used to resolve details, then vessel visibility is improved, but radiation dose increases and imaging time increases
Solution Approach 1:
The system performs preliminary action by acquiring high-contrast CINE images before the intervention procedure to establish a baseline model of the vessel and guide wire positions. This preliminary modeling allows the system to predict and compensate for motion effects during the actual fluoroscopy-guided intervention, resolving the contradiction between rapid imaging and clear visualization.
Solution Approach 2:
The patent creates a computational copy or representation of the vessel and guide wire positions based on phase-dependent motion modeling. This virtual model serves as a substitute for repeated high-dose CINE imaging during the intervention, allowing real-time monitoring without requiring continuous high-contrast radiation exposure.
3Device complexity
If conventional tracking methods are used without phase-dependent modeling, then device complexity is reduced, but tracking accuracy deteriorates due to cardiac and breathing motions
Solution Approach 1:
The system transitions from static tracking to dynamic phase-dependent tracking by incorporating temporal variation into the modeling framework. The guide wire and vessel positions are modeled as functions of physiological phase (cardiac and breathing cycles), allowing the system to adapt to motion dynamics and maintain high tracking accuracy throughout the intervention procedure.
Solution Approach 2:
The system performs preliminary action by acquiring high-contrast CINE images before the intervention procedure to establish a baseline model of the vessel and guide wire positions. This preliminary modeling allows the system to predict and compensate for motion effects during the actual fluoroscopy-guided intervention, resolving the contradiction between rapid imaging and clear visualization.
Data Source
AI summary
A periodic time-varying model of a guide wire, other device, or vessel is created from higher contrast CINE acquisition. A multivariate curve regression is used for periodic, phase dependent motion modeling. This model is then used to locate or track the guide wire, other device or vessel in lower contrast fluoroscopy images during intervention.


