Phase Sensitive Inversion Recovery MRI Reconstruction
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Solution Overview
Problem
Phase sensitive inversion recovery (PS-IR) magnetic resonance imaging techniques require prolonged scan times due to the need for separate phase reference data acquisition, which increases the overall imaging time without significantly improving signal-to-noise ratio (SNR) and is less efficient than non-PS methods.
Innovation Solution
Acquiring phase reference images with lower spatial resolution than IR-prepared images, allowing for PS-IR image reconstruction within the same cardiac R-R intervals as IR-prepared data acquisition, while interleaving or sequentially acquiring data across multiple R-R intervals to reduce overall scan time.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If phase reference data is acquired in separate non-IR-prepared R-R intervals, then phase reference information can be obtained, but total scan time is significantly prolonged
Solution Approach 1:
The patent combines phase reference data acquisition with IR-prepared data acquisition by acquiring both types of data during the same R-R interval. This merging eliminates the need for separate phase reference scans and significantly reduces total scan time while maintaining phase reference accuracy through simultaneous acquisition of reference and IR-prepared k-space data
Solution Approach 2:
The patent performs preliminary phase reference data acquisition during the same R-R interval before IR-prepared data acquisition. By preparing the phase reference information in advance within the same cardiac cycle, the system avoids the time penalty of separate reference scans while ensuring accurate phase reference is available for PS-IR reconstruction
2Reliability
If 2 R-R interval scan is used for PS-IR imaging, then image SNR is improved, but scan time is doubled
Solution Approach 1:
The patent merges SNR enhancement with reduced scan time by acquiring both IR-prepared and phase reference data during the same R-R interval. This combination allows the system to maintain high image SNR through proper magnetization recovery while eliminating the need to double scan time for separate reference acquisition
Solution Approach 2:
The patent ensures continuous useful action by acquiring phase reference data and IR-prepared data within the same R-R interval without interruption. This continuous acquisition strategy maintains magnetization recovery efficiency while maximizing data collection within each cardiac cycle, achieving both high SNR and scan time efficiency
3Manufacturing precision
If phase reference image is acquired with same spatial resolution as IR-prepared image, then image quality is maintained, but scan time increases significantly
Solution Approach 1:
The patent applies local quality by acquiring phase reference data at lower spatial resolution than the IR-prepared data. This localized resolution reduction is applied specifically to the phase reference acquisition, allowing sufficient phase information to be obtained while significantly reducing the scan time required for reference data collection
Solution Approach 2:
The patent uses partial action by acquiring only the necessary phase reference information at reduced resolution rather than full resolution. This partial acquisition approach provides sufficient phase reference data for PS-IR reconstruction while avoiding the time cost of acquiring complete high-resolution reference images
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach reduces the scan time penalty for PS-IR imaging by maintaining image quality and SNR, allowing for more efficient acquisition of phase-sensitive inversion recovery images with minimal increase in total scan time compared to non-PS methods.
Implementation Method 1
waiting a time called inversion time (TI), during which longitudinal magnetization recovers due to T1 relaxation
Implementation Method 2
magnetic resonance imaging
Data Source
AI summary
A system and method for cardiac magnetic resonance imaging (MRI) is disclosed that facilitates the phase sensitive reconstruction of inversion recovery magnetization prepared data with minimal scan time penalty by acquiring the phase reference data with low spatial resolution. The technique can be applied for the investigation of myocardial tissue characterization by acquiring 2D and/or 3D late Gadolinium enhancement (LGE) scans after the injection of a Gadolinium contrast agent. Regional areas of contrast accumulation in scarred myocardial tissue appear bright on these T1-weighted images. As disclosed here the proposed technique for phase sensitive inversion recovery acquisition with low resolution phase reference is robust against changes in inversion time, change in T1 due to Gadolinium contrast washout, high signal-to-noise ratio, and low scan time penalty compared to magnitude LGE.