Phosphate Ester Co-Surfactant for O/W Emulsion Viscosity
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Solution Overview
Problem
Oil-in-water (O/W) emulsions with low viscosity often experience stability issues, particularly at elevated temperatures, necessitating agents that reduce viscosity without compromising storage stability.
Innovation Solution
Incorporating a phosphate ester surfactant as a co-surfactant in topical compositions with polyglyceryl fatty ester surfactants to reduce viscosity while maintaining long-term thermal stability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If the viscosity of O/W emulsion is reduced to improve ease of operation, then the storage stability deteriorates at elevated temperatures
Solution Approach 1:
The patent combines polyglyceryl fatty ester surfactant with phosphate ester co-surfactant to create a composite surfactant system. This composite approach allows the formulation to achieve both low viscosity and high thermal stability, as the synergistic interaction between the two surfactant types resolves the contradiction between ease of application and storage stability.
Solution Approach 2:
The patent optimizes the concentration ratio of polyglyceryl fatty ester to phosphate ester co-surfactant within specific ranges (polyglyceryl fatty ester: 0.1-10 wt.%, phosphate ester: 0.01-3 wt.%). By adjusting these parameters, the formulation achieves the desired balance between low viscosity for easy application and sufficient viscosity for storage stability at elevated temperatures.
2Stability of the object's composition
If polyglyceryl fatty ester surfactant concentration is increased to improve stability, then viscosity increases reducing ease of operation
Solution Approach 1:
The phosphate ester co-surfactant acts as an intermediary that enhances the thermal stability provided by polyglyceryl fatty ester surfactant without significantly increasing viscosity. This intermediary component allows the system to achieve high stability while maintaining low viscosity for easy application.
Solution Approach 2:
The patent specifies optimal concentration ranges where polyglyceryl fatty ester is present at 0.1-10 wt.% and phosphate ester at 0.01-3 wt.%. Within these parameter ranges, the system achieves maximum thermal stability while maintaining viscosity levels that ensure ease of application, thus resolving the contradiction between stability and ease of operation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The addition of a phosphate ester surfactant effectively reduces viscosity by up to 50% without affecting thermal stability, achieving viscosities of 50,000 mPas or less after 10 days of storage at room temperature, even at elevated temperatures.
Implementation Method 1
topical compositions in the form of an oil-in-water (O/W) emulsion comprising an oil phase dispersed in an aqueous phase in the presence of a polyglyceryl fatty ester surfactant, characterized in that the topical composition further comprises a phosphate ester co-surfactant
Data Source
AI summary
The present invention relates to topical compositions in the form of an oil-in-water (O/W) emulsion comprising an oil phase dispersed in an aqueous phase in the presence of a polyglyceryl fatty ester surfactant, characterized in that the topical composition further comprises a phosphate ester co-surfactant. Furthermore, the invention relates to the use of a phosphate ester surfactant to reduce the viscosity of a topical composition in the form of an O/W emulsion comprising an oil phase dispersed in an aqueous phase in the presence of a polyglyceryl fatty ester surfactant.