Phosphite Salts Inhibit Mycotoxin Contamination in Cereals

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Solution Overview

Problem

Current methods for reducing mycotoxin contamination, particularly deoxynivalenol (DON), in cereals are insufficient, as controlling pathogenic fungi alone does not adequately prevent DON contamination, and existing fungicidal agents often fail to maintain levels below the standard value of 1.1 ppm.

Innovation Solution

A composition containing ammonium salts, primary to quaternary ammonium salts, alkali metal salts, alkaline earth metal salts, and polyvalent metal salts of phosphorous acid and phosphite ester is applied to cereals, either alone or in combination with fungicidal agents, to effectively inhibit DON contamination.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional fungicidal agents (triazole or methoxyacrylate type) are used to control pathogenic fungi, then the protection effect against Fusarium head blight is improved, but the DON contamination amount is not sufficiently reduced below the standard value

Engineering Contradiction:
Improveprotection effect against pathogenic fungiVSAvoidDON contamination amount
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent combines two different fungicidal agents with distinct mechanisms of action: a triazole type agent (inhibiting sterol biosynthesis) and a methoxyacrylate type agent (inhibiting respiratory activity or electron transfer). This composite approach targets multiple physiological pathways of the fungi, achieving synergistic suppression of both fungal growth and DON production, thereby resolving the contradiction between fungal protection and toxin reduction

Inventive Principle:
Principle #40Composite materials

2Reliability

If rotation spray with multiple fungicidal agents is performed to protect against complex infection, then the disease protection is improved, but the DON contamination amount remains above the standard value

Engineering Contradiction:
Improvedisease protectionVSAvoidDON contamination amount
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

Instead of sequential rotation spraying, the patent merges the application of triazole type and methoxyacrylate type fungicidal agents into a single combined treatment. This simultaneous application ensures both agents act together on the fungal population, maximizing the suppression of DON production while maintaining disease protection, thereby overcoming the limitation of rotation spray methods

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS8197832B2Methods and compositions for inhibiting mycotoxin contamination in cereals
Publication Date: 2012.06.12 MITSUI CHEM AGRO INC
  • US8197832B2 patent drawing
  • US8197832B2 patent drawing

AI summary

We search for a cultivation method for reducing the amount of mycotoxin contamination in wheat which has been an important pending question for the quality in actual producing field of wheat and the health hazard risk for customers.The present invention discloses a method of reducing the contamination amount of mycotoxin in cereals characterized in that one or more compounds A selected from the group consisting of ammonium salts, primary to quaternary ammonium salts, alkali metal salts, alkaline earth metal salts and polyvalent metal salts of phosphorous acid and phosphite ester are given to the cereals.