Phosphorylcholine Polymer Oral Composition for Dentin Hypersensitivity
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Solution Overview
Problem
Current methods for reducing dentinal hypersensitivity, such as those using aluminum lactate or potassium nitrate, are limited in consumer accessibility and effectiveness, with potassium nitrate having solubility issues and unpleasant tastes, while existing phosphorylcholine-containing polymer technologies require professional application or have ingredient limitations.
Innovation Solution
An oral composition containing a phosphorylcholine-containing polymer, specifically homopolymers or copolymers of 2-methacryloyloxyethyl phosphorylcholine, with a weight-average molecular weight of 10,000 to 10,000,000, combined with ingredients like glycerin or sorbitol, that can be used by general consumers to reduce dentinal hypersensitivity through direct application in the oral cavity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If aluminum lactate or potassium nitrate is used to reduce dentinal hypersensitivity, then the sensitivity reduction effect is achieved, but the taste becomes bitter, astringent, or harsh
Solution Approach 1:
The patent changes the chemical composition parameter from traditional aluminum lactate or potassium nitrate to a phosphorylcholine-containing polymer, which fundamentally alters the taste profile while maintaining the hypersensitivity reduction effect through a different mechanism of action
Solution Approach 2:
The invention uses a composite formulation combining the phosphorylcholine-containing polymer with specific flavoring agents and sweeteners to create a composition that both reduces hypersensitivity and masks any unpleasant tastes, transforming the overall sensory experience
2Reliability
If potassium nitrate is used in combination with sodium lauryl sulfate, then the hypersensitivity reduction is achieved, but the solubility decreases and precipitation occurs at low temperature
Solution Approach 1:
The patent changes the chemical structure of the active ingredient from ionic potassium nitrate to a polymer-based phosphorylcholine compound, which has different solubility characteristics and does not precipitate when combined with surfactants like sodium lauryl sulfate across a wide temperature range
3Reliability
If phosphorylcholine-containing polymer is used for dentin hypersensitivity reduction, then the sensitivity reduction and moisturizing effects are achieved, but the application requires professional intervention
Solution Approach 1:
The invention formulates the phosphorylcholine-containing polymer in a consumer-friendly oral composition format (toothpaste, mouthwash, or dental rinse) that can be easily applied by consumers themselves during routine oral hygiene, eliminating the need for professional dental application
Solution Approach 2:
The composition serves multiple functions simultaneously: reducing dentin hypersensitivity, providing moisturizing effects, and being suitable for routine consumer use, making it a versatile product that addresses multiple needs in a single formulation
4Reliability
If traditional methods are used to protect dentinal tubule, then the stimulus transmission is blocked, but the methods cannot be utilized routinely by general consumers
Solution Approach 1:
The patent creates a self-applied oral composition that consumers can use independently at home to protect their dentinal tubules, replacing professional procedures with a consumer-friendly routine treatment that maintains effective stimulus blockage
Data Source
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AI summary
An oral composition for reducing dentinal hypersensitivity according to the present invention comprises a phosphorylcholine-containing polymer as an active ingredient. A general consumer can use the oral composition routinely in various forms. The oral composition is brought into contact with an oral cavity of a user to reduce the dentinal hypersensitivity.