Photometry Analysis Chip Wavelength Correction Using a Color Plate
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Solution Overview
Problem
Existing analysis apparatuses suffer from reduced measurement accuracy due to variations in the central wavelength of the light source during sequential measurements of the reaction state and measurement wavelength, leading to inaccurate quantitative analysis.
Innovation Solution
Incorporation of a color plate within the imaging range of the analysis apparatus that changes reflectivity with wavelength, allowing simultaneous measurement of the reaction and wavelength variation, and a processor that corrects the measurement value based on detected wavelength variations.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If sequential measurement of reaction state and measurement wavelength is performed, then the analysis apparatus can perform quantitative analysis, but measurement accuracy decreases due to central wavelength variation between measurements
Solution Approach 1:
The patent combines the measurement of reaction state and detection of measurement wavelength into a single simultaneous operation by capturing an image that includes both the reaction region and the color plate. This eliminates the time sequence between measurements that causes central wavelength variation, thereby maintaining high measurement accuracy while performing both functions in one step.
Solution Approach 2:
The patent introduces a color plate as an intermediary element within the imaging range that reflects measurement light with wavelength-dependent characteristics. This color plate serves as a reference that allows simultaneous detection of the measurement wavelength alongside the reaction state measurement, enabling correction of wavelength variations without requiring separate measurement steps.
2Measurement precision
If a color plate is added to enable simultaneous wavelength detection, then measurement accuracy improves, but device complexity increases
Solution Approach 1:
The color plate serves multiple functions: it acts as a wavelength reference, provides reflectivity characteristics for measurement, and enables simultaneous detection of both reaction state and wavelength within the same imaging range. This multi-functionality allows the system to achieve improved measurement accuracy without requiring separate complex subsystems for wavelength detection.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Ensures high-accuracy quantitative analysis by compensating for changes in central wavelength and illuminance, thereby maintaining precise measurement accuracy despite variations in light source characteristics.
Implementation Method 1
a color plate that is arranged within the imaging range, that has a region irradiated with the measurement light, that has characteristics in which a reflectivity changes in accordance with a wavelength of incident light
Data Source
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AI summary
An analysis apparatus (100) includes: a support section (62) that supports, at a measurement position, an analysis chip (12) having a reaction region (12A), which holds a reagent, and used for quantitative analysis of reaction with a detection target substance that reacts with the reagent; a photometry unit (70) including a light-emitting element that irradiates the reaction region of the analysis chip with measurement light for measuring the reaction, and an area sensor that captures an image of a predetermined imaging range including the reaction region irradiated with the measurement light; and a color plate (75) that is arranged within the imaging range, that has a region irradiated with the measurement light, that has characteristics in which a reflectivity changes in accordance with a wavelength of incident light of the measurement light, and that is used for detecting a wavelength variation of the measurement light.