Photon-Number-Resolving Imaging for Super-Resolution of Unknown Sources

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Conventional passive optical super-resolution techniques face challenges in resolving uncontrolled light sources with unknown centroid, unequal brightness ratios, and multiple sources, degrading performance and imposing stringent alignment requirements.

Innovation Solution

Employing a photon-number-resolving (PNR) camera or detector to enhance imaging systems by providing additional photon number distribution information, enabling independent identification of light sources and overcoming the diffraction limit through photon enumeration techniques.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional passive optical super-resolution techniques are used, then spatial resolution can be improved beyond diffraction limit, but performance degrades significantly in cases of unknown centroid, unequal brightness ratios, and multiple sources

Engineering Contradiction:
Improvespatial resolutionVSAvoidperformance stability under unknown conditions
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

The patent changes the detection parameter from mean intensity to photon number distribution. By measuring the full photon statistics (PND) rather than just average intensity, the system gains ability to distinguish between multiple sources with unknown properties, resolving the contradiction between resolution improvement and performance stability under unknown conditions

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent introduces photon number distribution as an intermediary measurement that bridges the gap between raw optical data and source identification. This intermediate representation contains sufficient information to characterize sources regardless of their centroid position, brightness ratio, or number, thereby improving both resolution and adaptability

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If conventional super-resolution techniques are used, then resolution can be improved, but stringent alignment and centering conditions are required

Engineering Contradiction:
Improvespatial resolutionVSAvoidalignment requirements
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system performs self-alignment by automatically determining source positions and characteristics from the photon number distributions without requiring external alignment procedures. The algorithm inherently handles unknown centroids and relative positions, eliminating the need for manual alignment and centering operations

Inventive Principle:
Principle #25Self-service

3Loss of information

If photon number resolving detection is used, then additional information about light sources can be obtained, but device complexity increases

Engineering Contradiction:
Improveinformation completenessVSAvoiddetector complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The patent replaces complex mechanical alignment systems with a computational approach that processes photon number distribution data. Instead of using mechanically complex alignment procedures, the system uses algorithms to extract source information from the statistical photon counts, thereby reducing operational complexity while maintaining high information completeness

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Achieves sub-nm scale resolution of up to five fluorophores and an order of magnitude improvement in resolution for bright thermal states, allowing for robust super-resolution imaging without stringent alignment conditions.

Implementation Method 1

photon enumeration (S-RIPE) technique that uses a photon number resolving (PNR) camera

Methodology Applied
Scientific EffectPhoton enumeration: Photoelectric Effect

Data Source

PatentUS20250225615A1Super-resolution imaging via photon enumeration
Publication Date: 2025.07.10 THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
  • US20250225615A1 patent drawing
  • US20250225615A1 patent drawing
  • US20250225615A1 patent drawing

AI summary

A method of super-resolving light sources includes obtaining photon number distributions for each pixel of a spatial image by a photon-number-resolving device, and resolving positions and intensities of imaged light sources via analysis of joint spatial and photon-number-resolving data.