Photonic Biosensor Chip and Reader for Portable Multiplexed Diagnostics
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Solution Overview
Problem
Existing biosensors for analyte detection are invasive, costly, and require bulky lab equipment, making them unsuitable for efficient point-of-care diagnostics.
Innovation Solution
A portable photonic biosensor device with a photonic sensor chip and reader device for multiplexed diagnostics, utilizing a photonic sensor chip with resonators and a microfluidic assembly to detect multiple analytes in a single sample, providing an inexpensive, reusable, and scalable diagnostic solution with enhanced specificity and sensitivity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If existing biosensor techniques are used for analyte detection, then detection capability is achieved, but the equipment becomes bulky and expensive requiring lab infrastructure
Solution Approach 1:
The system divides the biosensing function into separate modular components: disposable sensor cartridges containing the sensing element and reusable reader devices. This segmentation allows the complex detection capability to be packaged in small, portable units that can be used outside traditional lab settings while maintaining analytical performance.
Solution Approach 2:
The patent replaces traditional mechanical/bulky lab equipment with photonic sensing technology that uses light interaction with analytes. The photonic sensors detect analytes through optical property changes rather than requiring large mechanical measurement systems, enabling miniaturization and portability while maintaining detection precision.
2Measurement precision
If traditional biosensor methods are employed, then analyte measurement is possible, but the process becomes time-consuming and invasive
Solution Approach 1:
The sensor cartridges are pre-prepared with sensing elements and reagents before use. Sample collection and preparation steps are minimized and standardized, allowing rapid analysis. The system performs measurements quickly without requiring extensive sample processing or waiting periods, reducing overall diagnostic time while maintaining accuracy.
3Measurement precision
If conventional biosensor systems are used, then detection function is provided, but the cost becomes high reducing accessibility
Solution Approach 1:
The system uses disposable sensor cartridges that are inexpensive to manufacture and discard after a single use. This approach eliminates the need for expensive, complex reusable sensor systems while maintaining detection accuracy. The low cost of disposable cartridges makes the technology accessible for point-of-care and resource-limited settings.
Solution Approach 2:
The reusable reader device can interface with multiple types of sensor cartridges through standardized connection protocols. This universality allows a single expensive component to serve many functions across different analyte types, amortizing the cost and improving overall system accessibility and value.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables efficient, low-cost, and portable detection of multiple analytes at the point-of-care with high specificity and sensitivity, overcoming the limitations of traditional biosensors.
Implementation Method 1
the photonic sensor chip includes one or more resonators, wherein the one or more resonators is substantially in contact with at least a fluid
Implementation Method 2
the reader device includes at least a light source and the reader device is configured to provide an input optical signal using the at least a light source
Data Source
AI summary
An apparatus for photonic biosensors for multiplexed diagnostics and a method of use are disclosed. The apparatus includes a portable device configured for point-of-care diagnostics. The portable device includes a photonic sensor chip that includes one or more resonators that is substantially in contact with at least a fluid that includes one or more analytes and the reader device communicatively connected to the photonic sensor chip that includes at least a light source and the reader device is configured to provide an input optical signal using the at least a light source, receive the one or more sensor signals from the photonic sensor chip and determine one or more characteristics of the one or more analytes as a function of the one or more sensor signals and a connecting system, wherein the connecting system is configured to connect the photonic sensor chip and the reader device.