Photoresponsive Sensor Module Layout for Probe State Verification
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Solution Overview
Problem
Existing sensor technologies lack a reliable method to inspect the presence or absence of probe molecules on a sensor chip before measurement, leading to potential sensitivity loss and erroneous detection due to buffer ion residues, which conventional methods fail to distinguish from probe molecule signals.
Innovation Solution
A sensor module system comprising a first sensor module with probe molecules and a second sensor module without probe molecules, utilizing light response to differentiate between buffer ion residues and probe molecule states, allowing non-destructive and non-contact inspection.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional sensor measurement methods are used, then probe molecule signals can be detected, but buffer ion residues cannot be distinguished leading to erroneous detection
Solution Approach 1:
The detection system is segmented into two separate sensor modules: a first sensor module with probe molecules for detecting target substances, and a second sensor module without probe molecules for detecting buffer ion residues. This segmentation allows independent measurement of probe molecule signals and buffer ion interference, enabling distinction between the two and eliminating erroneous detection.
2Measurement precision
If sensor chip inspection is performed before measurement, then probe molecule presence can be confirmed, but buffer ion residue interference remains undetected
Solution Approach 1:
The second sensor module acts as an intermediary device that specifically measures buffer ion residue levels. By introducing this intermediary measurement capability, the system can identify and account for buffer ion interference that would otherwise contaminate the probe molecule detection signals, enabling accurate inspection before measurement.
3Device complexity
If a single sensor module is used, then device complexity is minimized, but the ability to differentiate between buffer ions and probe molecules is lost
Solution Approach 1:
The single sensor module is divided into two distinct modules with different functional characteristics. The first module contains probe molecules and detects both target substances and buffer ions. The second module lacks probe molecules and detects only buffer ions. This segmentation enables signal differentiation while maintaining relatively simple device architecture.
Solution Approach 2:
Different local qualities are assigned to the two sensor modules: the first module has probe molecules attached to its sensitive film, while the second module has no probe molecules. This local quality difference enables each module to perform specialized detection functions, with the second module serving as a reference for buffer ion levels.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables accurate confirmation of probe molecule state while eliminating buffer ion residue noise, maintaining sensitivity and preventing erroneous detection, with the system capable of repeated use through chip replacement and automated cleaning.
Implementation Method 1
a first sensor module including a probe molecule that responds to light irradiation with charge
Data Source
AI summary
According to one embodiment, a sensor module system includes a first sensor module including a probe molecule that responds to light irradiation with charge, and a second sensor module including no probe molecule. A first flow path is connected to one end side of the first sensor module, and a second flow path is connected to the other end side. A third flow path branching from the first flow path is connected to one end side of the second sensor module, and a fourth flow path joining the first flow path is connected to the other end side. A valve capable of opening and closing the third flow path is connected to a junction of the first flow path and the third flow path.