Phototherapy Device with Random Pulse Control

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Solution Overview

Problem

Phototherapy effectiveness decreases over time due to the operation of a protective homeostasis mechanism, which limits the duration and efficacy of long-term treatments.

Innovation Solution

A phototherapy device employing a drive pulse train with a constant pulse period and random fluctuation, limited optical radiant power density, rest intervals, and a duty ratio, along with near-infrared light emitting diodes, to maintain treatment effects over extended periods by mitigating the protective mechanism of homeostasis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If phototherapy is administered continuously for a long period, then treatment duration is extended, but phototherapy effectiveness decreases rapidly

Engineering Contradiction:
Improvetreatment durationVSAvoidphototherapy effectiveness
Core Design Contradiction:
Duration of action of moving objectVSReliability

Solution Approach 1:

The patent implements periodic action by alternating between pulse fluctuation periods and rest intervals. During pulse fluctuation periods, the light source operates with varying pulse widths to maintain effectiveness, then transitions to rest intervals where it is turned off completely. This periodic on-off pattern prevents the protective homeostasis mechanism from activating, thereby maintaining phototherapy effectiveness over extended treatment durations.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent applies dynamics by making the pulse width variable rather than fixed. During pulse fluctuation periods, the pulse width is randomly determined within a range, creating dynamic variation in the light delivery pattern. This dynamic adjustment prevents adaptation by the protective mechanism and maintains therapeutic effectiveness throughout the treatment course.

Inventive Principle:
Principle #15Dynamics

2Reliability

If the light source operates continuously to maintain treatment effect, then therapeutic efficacy is preserved, but the protective homeostasis mechanism activates and reduces effectiveness

Engineering Contradiction:
Improvetherapeutic efficacyVSAvoidprotective homeostasis mechanism
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent uses periodic action by implementing rest intervals where the light source is completely turned off between pulse fluctuation periods. This periodic cessation prevents the protective homeostasis mechanism from detecting and responding to continuous light exposure, thereby eliminating the harmful effect while maintaining therapeutic efficacy during the active treatment periods.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent segments the treatment into distinct pulse fluctuation periods and rest intervals. By dividing the continuous treatment into segmented on-off cycles, the system maintains therapeutic effectiveness during pulse delivery while allowing the protective mechanism to remain inactive during rest intervals, thus preventing its activation.

Inventive Principle:
Principle #1Segmentation

3Reliability

If random pulse periods and rest intervals are implemented to inhibit homeostasis, then phototherapy effectiveness is maintained, but device control complexity increases

Engineering Contradiction:
Improvephototherapy effectivenessVSAvoidcontrol mechanism
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies parameter changes by randomly determining pulse widths within a predefined range and randomly determining rest interval durations within another range. Instead of using complex adaptive algorithms, the system varies simple temporal parameters (pulse width and rest interval) randomly, which effectively inhibits the protective homeostasis mechanism while keeping the control logic relatively simple and implementable.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution maintains phototherapy effectiveness over long periods by inhibiting the protective homeostasis mechanism, ensuring consistent biological responses and systemic reactions.

Implementation Method 1

phototherapy technique may cause photons to collide with cytochrome c oxidase (CCO) molecules in mitochondria to convert adenosine monophosphate (AMP) into high-energy adenosine diphosphate (ADP)

Methodology Applied
Scientific EffectPhototherapy: Photo-oxidation

Implementation Method 2

a first light emitting diode configured to radiate red light having a peak wavelength of 660 nm±2% and a second light emitting diode configured to radiate near-infrared light having a peak wavelength of 830 nm±2%

Methodology Applied
Scientific EffectLight emission: Light Emitting Diode

Data Source

PatentUS20240335674A1Phototherapy device and control method therefor
Publication Date: 2024.10.10 INHA UNIV RES & BUSINESS FOUNDATION
  • US20240335674A1 patent drawing
  • US20240335674A1 patent drawing
  • US20240335674A1 patent drawing

AI summary

A technology relating to a phototherapy device is disclosed. A therapeutic light source for outputting red light having a peak wavelength in the range of 660 nm±2% is driven by a driving pulse train having a constant pulse period during a pulse fluctuation period. The pulse period is randomly determined within a first range for each pulse fluctuation period. The optical radiant power density of a red wavelength band may be limited to be within the range of 20-100 mW/cm2-cm. A pause period of a random length in which the light source is turned off may be interposed between pulse fluctuation periods. In addition, the driving pulse train outputted during the pulse fluctuation period may have a randomly determined duty ratio.