Purified Hydrogen Peroxide Gas Exposure for In-Situ Respiratory Protection

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Solution Overview

Problem

Existing air handling systems in enclosed spaces are ineffective in removing pathogens, allergens, and parasites that are too heavy to traverse, and current methods for generating purified hydrogen peroxide gas (PHPG) do not address the need for in-situ treatment of air in environments during health crises or epidemics, limiting the prevention and mitigation of respiratory infections.

Innovation Solution

Generating and maintaining a concentration of purified hydrogen peroxide gas (PHPG) at 0.01 parts per million in enclosed spaces, free of hydration and ozone, to enhance the production of hypothiocyanate ions in the respiratory system, thereby improving respiratory health and reducing infection transmission.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current air handling systems use UV light, ozone, and other activated oxygen species to neutralize pathogens, then airborne pathogens can be killed or neutralized, but pathogens, allergens, and parasites that are too heavy to traverse the system are missed and remain untreated

Engineering Contradiction:
Improvepathogen elimination effectivenessVSAvoidability to treat all types of pathogens
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The invention divides the air treatment process into two segments: (1) HVAC systems treat airborne pathogens through filtration and UV irradiation, and (2) PHPG generators treat all pathogens including heavy particles on surfaces and in the air. This segmentation allows each system to address its optimal target population without relying on the other to handle all pathogen types.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention introduces PHPG (purified hydrogen peroxide gas) as an intermediary substance that bridges the gap between HVAC air handling and direct environmental disinfection. PHPG serves as a mediator that can penetrate and treat areas and pathogen types that traditional HVAC systems cannot reach, particularly heavy particles and surface contaminants.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If HVAC systems pass contaminated air through enclosed systems with UV light and ozone, then airborne pathogens can be neutralized, but the systems require air to pass through them to be effective

Engineering Contradiction:
Improvepathogen neutralization capabilityVSAvoidsystem operational requirements
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The PHPG generation system operates autonomously by converting ambient air into PHPG through photocatalytic reactions on the reactor surface. The system serves itself by using natural sunlight or UV lighting to drive the chemical conversion of oxygen and water vapor in the air into hydrogen peroxide gas, eliminating the need for external power sources or complex operational controls.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The invention replaces the mechanical air forcing mechanism of HVAC systems with a chemical conversion process. Instead of mechanically moving and filtering air through complex ductwork and filtration systems, the PHPG generator uses photocatalytic chemistry to transform ambient air components into disinfecting PHPG that is then released into the environment.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Adaptability or versatility

If PHPG is used to treat environments during health crises and epidemics, then in-situ treatment of air and surfaces can be achieved, but current methods do not provide sufficient concentration or purity control

Engineering Contradiction:
Improvein-situ treatment capabilityVSAvoidPHPG concentration and purity control
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The invention controls PHPG concentration and purity by adjusting key parameters: (1) UV light intensity and wavelength to optimize photocatalytic efficiency, (2) ambient humidity levels to control water vapor availability for H2O2 formation, (3) reactor surface area and material composition to enhance PHPG generation rate, and (4) air flow rate through the reactor to balance conversion efficiency with output concentration.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system incorporates feedback mechanisms to maintain optimal PHPG generation: (1) UV sensors monitor the intensity and wavelength of the light source to ensure consistent photocatalytic activity, (2) humidity sensors track ambient moisture levels to adjust operational parameters, and (3) the system automatically adjusts air flow and UV power to maintain target PHPG concentrations in the released gas.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method effectively reduces the severity and transmission of respiratory infections, enhances lung function, and stimulates host defenses by increasing hypothiocyanate ion levels, even with intermittent exposure to PHPG environments.

Implementation Method 1

enhance the production of hypothiocyanate ions in the respiratory system

Methodology Applied
Scientific EffectHypothiocyanate ion production: Chemical Bonding

Implementation Method 2

purified hydrogen peroxide gas (PHPG) that is free of hydration and ozone

Methodology Applied
Scientific EffectHydrogen peroxide reaction: Oxidation

Data Source

PatentUS12472208B2Methods for improving respiratory system health and increasing the concentration of hypothiocyanate ion in vertebrate lungs
Publication Date: 2025.11.18 SYNEXIS LLC
  • US12472208B2 patent drawing
  • US12472208B2 patent drawing
  • US12472208B2 patent drawing

AI summary

The present disclosure relates to methods and devices to improve respiratory system health, increase resistance to infection, and increase the hypothiocyanate ion in mammalian lungs. The methods generally comprise: generating a Hydrogen Peroxide Gas that is non-hydrated and free of ozone, and directing the gas comprising primarily Hydrogen Peroxide Gas into an environment and exposing a subject to the environment such that the Hydrogen Peroxide Gas acts to the increase of the hypothiocyanate ion in mammalian lungs.