Physiological Data Textual Representation for Clinical Hypothesis Generation

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Solution Overview

Problem

In intensive care units, physicians face information overload due to the high dimensionality of physiological data, making it difficult to detect subtle yet clinically meaningful correlations in real-time, leading to reactive rather than proactive medical interventions.

Innovation Solution

A method that converts physiological data into textual representations using natural language generation, allowing for the automatic generation of input terms for an information retrieval system to retrieve relevant information and generate hypotheses about a patient's medical condition, enabling proactive interventions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If physiological data is captured and stored in high dimensionality, then comprehensive patient information is available, but information overload occurs making it difficult to detect meaningful correlations

Engineering Contradiction:
Improvequantity of physiological dataVSAvoidease of detecting meaningful correlations
Core Design Contradiction:
Quantity of substanceVSEase of operation

Solution Approach 1:

The system extracts only the most relevant features from the high-dimensional physiological data using automated feature extraction algorithms. Instead of presenting all captured data to physicians, the system identifies and extracts meaningful patterns and correlations, reducing the data volume while preserving clinical significance. This resolves the contradiction by maintaining comprehensive data capture while extracting only the essential information for clinical decision-making.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces an intermediary computational layer between raw physiological data and clinical interpretation. This intermediary system uses natural language generation to convert numerical data into clinically relevant textual representations, and employs information retrieval systems to connect patient data with medical knowledge bases. This intermediary processing resolves the contradiction by bridging the gap between comprehensive data capture and meaningful clinical insight.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If manual integration of physiological data is performed, then comprehensive patient assessment is possible, but time consumption increases reducing productivity

Engineering Contradiction:
Improvecomprehensiveness of patient assessmentVSAvoidproductivity of physician
Core Design Contradiction:
Adaptability or versatilityVSProductivity

Solution Approach 1:

The system enables self-service by automatically performing data integration, feature extraction, and clinical hypothesis generation without requiring manual physician intervention. The automated system continuously monitors physiological data, extracts meaningful features, generates natural language descriptions, and proposes clinical hypotheses. This resolves the contradiction by maintaining comprehensive assessment capabilities while eliminating the time-consuming manual integration process, thereby increasing physician productivity.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system performs preliminary analysis of physiological data continuously in the background, preparing integrated patient assessments and potential clinical hypotheses before physicians need them. This preliminary processing ensures comprehensive data integration is already completed when physicians review patient cases, resolving the contradiction by providing thorough assessments without adding to physician workload or time consumption.

Inventive Principle:
Principle #10Preliminary action

3Reliability

If real-time analysis of physiological data streams is implemented, then proactive interventions become possible, but system complexity increases

Engineering Contradiction:
Improvetimeliness of medical interventionVSAvoidcomplexity of analysis system
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system segments the complex real-time analysis task into distinct modular components: data acquisition module, feature extraction module, natural language generation module, information retrieval module, and hypothesis generation module. Each module handles a specific aspect of the analysis pipeline independently. This segmentation resolves the contradiction by enabling real-time proactive analysis through coordinated simple modules rather than a single complex system, improving reliability while managing complexity through modular architecture.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS10395004B2Hypothesis-driven, real-time analysis of physiological data streams using textual representations
Publication Date: 2019.08.27 INTERNATIONAL BUSINESS MACHINE CORPORATION
  • US10395004B2 patent drawing
  • US10395004B2 patent drawing
  • US10395004B2 patent drawing

AI summary

A method of analyzing physiological data streams. According to the method, physiological data is received into a computerized machine. The physiological data comprises numerical data and medical symptoms of a patient. Features are extracted from the physiological data based on development of the physiological data over a period of time. The features are converted into a textual representation using natural language generation. Input terms for an information retrieval system operating on the computerized machine are automatically generated based on the features. The input terms are input to the information retrieval system. A corpus of data is automatically searched to retrieve results to the input terms using the information retrieval system.