Phytic Acid Electrolyte Composite for EHEC Disinfection

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Solution Overview

Problem

Current antimicrobial agents using phytic acid are ineffective against acid-resistant food poisoning bacteria like EHEC, requiring excessive amounts and lacking significant bactericidal activity.

Innovation Solution

A composition combining phytic acid with electrolytes such as sodium chloride, potassium chloride, or calcium chloride, which synergistically enhances bactericidal activity by forming chelates with multivalent ions, damaging the bacterial cell membrane and increasing permeability, thereby effectively killing EHEC within minutes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If phytic acid is used alone as an antimicrobial agent, then it has low bactericidal activity against acid-resistant bacteria like EHEC, but using excessive amounts is required which increases cost and potential harm

Engineering Contradiction:
Improvebactericidal activityVSAvoidamount of phytic acid
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent combines phytic acid with electrolytes (such as sodium chloride, potassium chloride, calcium chloride, or magnesium chloride) to create a composite antimicrobial composition. This composite approach allows the mixture to achieve synergistic effects where the electrolytes enhance the bactericidal activity of phytic acid, enabling effective killing of acid-resistant bacteria like EHEC at much lower concentrations of phytic acid compared to using it alone.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent changes the chemical environment parameters by introducing electrolytes that alter the ionic composition and conductivity of the antimicrobial solution. This parameter change enhances the ability of phytic acid to interact with bacterial cell membranes, improving its bactericidal effectiveness against acid-resistant bacteria without requiring excessive phytic acid concentration.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If high concentrations of phytic acid are used to achieve bactericidal activity, then antimicrobial effect improves, but the complexity of the composition and potential harmful effects increase

Engineering Contradiction:
Improveantimicrobial effectVSAvoidcomposition complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

By creating a composite composition of phytic acid and common electrolytes, the patent achieves effective antimicrobial action with a relatively simple formulation. The electrolytes used are common, safe substances that do not significantly increase composition complexity, yet they dramatically improve the bactericidal activity against acid-resistant bacteria.

Inventive Principle:
Principle #40Composite materials

3Reliability

If phytic acid is used to disinfect acid-resistant bacteria, then it requires excessive amounts, but this increases loss of substance and reduces efficiency

Engineering Contradiction:
Improvedisinfection efficacyVSAvoidphytic acid consumption
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The composite composition of phytic acid and electrolytes achieves synergistic antimicrobial effects, allowing disinfection of acid-resistant bacteria with minimal phytic acid consumption. The electrolytes act as enhancers that amplify the bactericidal activity, dramatically reducing the amount of phytic acid needed compared to using it alone.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The antimicrobial composition achieves significant bactericidal activity against acid-resistant EHEC and other food poisoning bacteria with minimal phytic acid usage, effectively controlling bacterial populations and maintaining efficacy across various conditions, including biofilms.

Implementation Method 1

synergistically enhances bactericidal activity by forming chelates with multivalent ions, damaging the bacterial cell membrane and increasing permeability

Methodology Applied
Scientific EffectChelation:

Data Source

PatentUS9635860B2Antimicrobial composition including phytic acid and electrolytes
Publication Date: 2017.05.02 KOREA UNIV RES & BUSINESS FOUND
  • US9635860B2 patent drawing
  • US9635860B2 patent drawing
  • US9635860B2 patent drawing

AI summary

The present invention relates to an antimicrobial composition including phytic acid and electrolytes.