Phyto-mixture for Skin Efflorescences Reducing Side Effects
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Solution Overview
Problem
Current synthetic pharmaceutical products for skin irritations and diseases often cause side effects and contribute to growing antimicrobial resistances, with limited natural alternatives offering both antibacterial and anti-inflammatory efficacy.
Innovation Solution
A phyto-mixture comprising plant extracts from the Asteraceae, Verbenaceae, and Burseraceae families, specifically Bidens, Stachytarpheta, and Bursera species, combined with Aloe vera and Stemodia maritima, providing antimicrobial and anti-inflammatory effects for the prevention and treatment of efflorescences.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If synthetic pharmaceutical products are used for treatment of skin irritations and diseases, then therapeutic efficiency is improved, but side effects and allergic reactions increase
Solution Approach 1:
The patent changes the chemical composition parameters by replacing synthetic active agents with plant-based extracts. The formulation uses extracts from Bidens, Stachytarpheta, and Bursera species, which have different chemical properties than synthetic drugs, thereby maintaining therapeutic efficiency while reducing side effects and allergic reactions.
Solution Approach 2:
The patent employs a composite phytopreparation combining multiple plant extracts (Bidens, Stachytarpheta, Bursera species) with specific excipients. This composite formulation synergistically combines the antimicrobial and anti-inflammatory properties of different plant sources to achieve reliable therapeutic effects while minimizing harmful side effects associated with single synthetic agents.
2Speed
If synthetic active agents are used for treatment, then immediate therapeutic effect is achieved, but antimicrobial resistances steadily grow
Solution Approach 1:
The patent changes the chemical nature of the active agents from synthetic to natural plant extracts. The multi-component phytopreparation contains various phytochemicals that act through multiple mechanisms, making it harder for microorganisms to develop resistance compared to single synthetic antimicrobial agents.
Solution Approach 2:
The patent converts the limitation of natural plant extracts (slower action than synthetic drugs) into a benefit by using combinations of multiple extracts that work synergistically. This approach provides sustained therapeutic effect while preventing resistance development, effectively turning the 'slowness' of natural remedies into a strategic advantage against resistant germs.
3Object-generated harmful factors
If plant extracts are used as natural alternatives, then side effects are reduced, but antimicrobial and anti-inflammatory efficiency is insufficient
Solution Approach 1:
The patent merges multiple plant extracts with proven antimicrobial and anti-inflammatory properties into a single phytopreparation. By combining Bidens extract (antimicrobial), Stachytarpheta extract (anti-inflammatory), and Bursera extract (antimicrobial), the formulation achieves synergistic effects that enhance overall efficiency while maintaining the low side effect profile of natural products.
Solution Approach 2:
The patent creates a composite phytopreparation that integrates multiple plant-based active ingredients with carefully selected excipients. This composite structure ensures both high antimicrobial and anti-inflammatory efficiency through the combined actions of different plant extracts, while maintaining biocompatibility and minimal side effects.
4Quantity of substance
If miscellaneous plants from traditional medicine are tested, then various ingredients are identified, but efficiency is less or none observed
Solution Approach 1:
The patent applies local quality by selecting specific species within plant families based on their proven therapeutic properties. Instead of using miscellaneous plants, the formulation specifically uses Bidens species for antimicrobial activity, Stachytarpheta species for anti-inflammatory effects, and Bursera species for additional antimicrobial coverage, ensuring each component contributes targeted therapeutic quality.
Solution Approach 2:
The patent changes the selection criteria from general traditional medicine plants to specifically selected species with documented bioactive compounds. The formulation uses extracts standardized for key active ingredients, ensuring consistent and reliable therapeutic efficiency rather than variable results from unselected traditional plants.
Data Source
AI summary
The present invention relates to an immunologically active phyto-mixture comprising at least one plant extract selected from the family (a) Asteraceae, (b) Verbenaceae, and/or (c) Burseraceae, preferably at least one plant extract from the genus (a) Bidens, (b) Stachytarpheta, and/or (c) Bursera. Particularly preferred species include (a) Bidens alba, Bidens pilosa, (b) Stachytarpheta jamaicensis, Stachytarpheta cayennensis, Stachytarpheta indica, and/or (c) Bursera simaruba, Bursera microphylla, Bursera glabrifolia. The phyto-mixture optionally comprises (d) at least one further biologically active plant extract, such as Aloe vera and/or Stemodia maritima. The afore-mentioned phyto-mixture according to the invention exhibits good antimicrobial and anti-inflammatory efficiency and is particularly suitable for prevention and treatment of efflorescences. Therefore, the present invention also relates to a preparation for oral and topical administration for prevention and treatment of efflorescences of the skin and the mucous membrane.