Picolinamide Fungicides Broad-Spectrum Pathogen Control

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Solution Overview

Problem

Current fungicides are not universally effective against various fungal pathogens and often require multiple applications, which can increase costs and complexity in agricultural use.

Innovation Solution

Development of picolinamide compounds, specifically formulated as fungicidal compositions for use in protecting plants against ascomycetes, basidiomycetes, deuteromycetes, and oomycetes, applied through various formulations such as solutions, dusts, or granules, to provide broad-spectrum fungal protection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current fungicides are used to protect plants against fungal pathogens, then some level of protection is achieved, but the fungicides are not universally effective against various fungal pathogens and require multiple applications

Engineering Contradiction:
Improvefungicidal effectivenessVSAvoidbroad-spectrum activity
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent develops picolinamide compounds that serve as universal fungicides effective against multiple fungal pathogen types including ascomycetes, basidiomycetes, deuteromycetes, and oomycetes. The chemical structure of the picolinamide compounds is designed to provide broad-spectrum activity across different fungal groups, allowing a single compound to perform multiple protective functions that previously required several different fungicides

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent modifies chemical parameters of the fungicide molecules by developing specific picolinamide derivatives with varied substituent groups (R1-R11 in Formula I). These parameter changes in molecular structure enhance both the reliability and versatility of the fungicides, enabling them to effectively target diverse fungal pathogens while maintaining low phytotoxicity

Inventive Principle:
Principle #35Parameter changes

2Reliability

If multiple fungicide applications are made to ensure comprehensive protection, then fungal control reliability improves, but costs and operational complexity increase

Engineering Contradiction:
Improvefungal control effectivenessVSAvoidapplication complexity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The picolinamide compounds are formulated to provide long-lasting broad-spectrum protection that reduces the frequency of applications needed. A single application of these enhanced fungicides can protect against multiple fungal pathogen types over an extended period, simplifying the application schedule and reducing operational complexity while maintaining reliable fungal control

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Adaptability or versatility

If multiple different fungicides are used to target various fungal pathogens, then coverage of different pathogen types improves, but the cost of fungicide programs increases

Engineering Contradiction:
Improvepathogen coverageVSAvoidtotal fungicide cost
Core Design Contradiction:
Adaptability or versatilityVSQuantity of substance

Solution Approach 1:

The patent merges the functions of multiple different fungicides into a single picolinamide compound that provides broad-spectrum activity. By combining protective effects against ascomycetes, basidiomycetes, deuteromycetes, and oomycetes into one chemical entity, the patent reduces the total quantity of fungicide substances needed and lowers overall program costs while maintaining comprehensive pathogen coverage

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The universal effectiveness of the picolinamide compounds against diverse fungal pathogens eliminates the need to purchase and apply multiple specialized fungicides. This multi-functionality translates directly to cost savings by reducing the total quantity of fungicide substances required in the agricultural program

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentEP3240408B1Picolinamides with fungicidal activity
Publication Date: 2020.04.08 DOW AGROSCIENCES LLC
  • EP3240408B1 patent drawing
  • EP3240408B1 patent drawing
  • EP3240408B1 patent drawing

AI summary

The invention relates to picolinamides of Formula I and their use as fungicides.