Pimaricin-Cyclodextrin Complex Beverage Preservative

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Solution Overview

Problem

Current beverage preservatives, such as benzoic acid, EDTA, and polyphosphates, pose health and environmental concerns due to their detrimental effects and instability, necessitating the development of alternative systems that are both effective and environmentally friendly.

Innovation Solution

A preservative system comprising a pimaricin-cyclodextrin complex, which enhances the solubility and stability of pimaricin, allowing it to inhibit yeast and mold growth in beverages for at least 16 weeks without compromising sensory attributes, and can be combined with povidone and DMDC for enhanced efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If benzoic acid and its salts are used as preservatives in beverages with vitamin C and high pH, then preservative effectiveness is improved, but benzene formation increases creating health risks

Engineering Contradiction:
Improvepreservative effectivenessVSAvoidbenzene formation
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent removes benzoic acid from the preservative system entirely, replacing it with pimaricin and its derivatives. This extraction of the harmful substance while maintaining preservative functionality through alternative natural antimicrobial agents directly resolves the benzene formation issue while preserving preservative effectiveness.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the chemical parameters of the preservative system by substituting benzoic acid with pimaricin, which has different chemical properties and does not undergo the harmful reaction with vitamin C to form benzene. This parameter change maintains preservative action through a different mechanism that is safe in the presence of ascorbic acid.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If EDTA is used as a preservative to sequester metal ions and inhibit microbial growth, then preservative effectiveness is improved, but environmental persistence and pollution increase

Engineering Contradiction:
Improvepreservative effectivenessVSAvoidenvironmental persistence
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent extracts EDTA from the preservative system and replaces it with pimaricin, a natural antimicrobial agent. This removal eliminates the environmental persistence and pollution problems associated with EDTA while maintaining preservative effectiveness through the natural biodegradability of pimaricin.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs pimaricin as a biodegradable, environmentally friendly preservative that breaks down naturally, contrasting with EDTA's persistent nature. This approach uses a short-lived, naturally degradable substance that does not accumulate in the environment, resolving the environmental persistence issue.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Reliability

If polyphosphates are used as preservatives to sequester metals, then preservative effectiveness is improved, but stability in aqueous solution deteriorates leading to sensory issues

Engineering Contradiction:
Improvepreservative effectivenessVSAvoidaqueous solution stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent removes polyphosphates from the preservative system and replaces them with pimaricin. This extraction eliminates the stability problems in aqueous solutions that lead to sensory degradation, while maintaining preservative effectiveness through pimaricin's natural antimicrobial properties that do not degrade in the same manner.

Inventive Principle:
Principle #2Taking out (Extraction)

4Reliability

If higher concentrations of sorbic acid are used to inhibit spoilage microorganisms, then preservative effectiveness is improved, but regulatory restrictions and sensory impact increase

Engineering Contradiction:
Improvepreservative effectivenessVSAvoidsensory impact
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent extracts sorbic acid from the preservative system and replaces it with pimaricin. This removal eliminates the sensory impact issues and regulatory restrictions associated with high concentrations of sorbic acid, while maintaining preservative effectiveness through pimaricin's natural antimicrobial activity at lower concentrations.

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The pimaricin-cyclodextrin complex effectively prevents spoilage in beverages by maintaining pimaricin's solubility and activity, ensuring a stable product for extended periods while avoiding the drawbacks of traditional preservatives, and when combined with other agents, provides broad-spectrum antimicrobial protection.

Implementation Method 1

a pimaricin-cyclodextrin complex; wherein the preservative system prevents spoilage

Methodology Applied
Scientific EffectInclusion complex formation: Absorption (physical)

Data Source

PatentEP2442678B1Beverage preservative system containing pimaricin - cyclodextrin complex
Publication Date: 2018.05.09 PEPSICO INC
  • EP2442678B1 patent drawingFigure 1
  • EP2442678B1 patent drawingFigure 2
  • EP2442678B1 patent drawingFigure 3

AI summary

The present invention provides a beverage preservative system comprising a pimaricin-cyclodextrin complex for use in beverages products. The present invention is further directed to beverage products comprising the beverage preservative systems. The beverage preservative system prevents spoilage by microorganisms in a beverage within a sealed container for a period of at least 16 weeks.