Disposable Pipette Resin Filter Radiation Sterilization
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Solution Overview
Problem
Existing disposable pipettes, such as those with cotton plugs, risk contaminating samples with foreign fibers, which is a concern in medical and biochemical fields where sample purity is critical.
Innovation Solution
A disposable pipette design featuring a resin-made pipette main body with a resin filter inserted into the connection portion, which is radiation-exposed to achieve a suppressed elution amount, ensuring minimal foreign matter contamination.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a cotton plug is inserted into the connection portion of the pipette main body to control the dropping amount, then the dropping amount can be facilitated to be controlled, but foreign matter (cotton fibers) may be mixed into the sample
Solution Approach 1:
The patent removes the cotton plug from the connection portion and replaces it with a resin filter. This extraction of the harmful cotton material eliminates the source of foreign fiber contamination while maintaining the filtering function through the resin-based alternative
Solution Approach 2:
The patent changes the material parameter from cotton to resin, specifically selecting resin materials with low elution rates under radiation exposure. This material substitution maintains the filtering function while eliminating the harmful fiber contamination issue
2Object-generated harmful factors
If a resin filter is used instead of a cotton plug to avoid foreign matter contamination, then foreign fiber mixing is prevented, but elution from the resin filter may occur during radiation exposure for sterilization
Solution Approach 1:
The patent specifies precise parameter requirements for the resin filter material, including elution rate limits (maximum absorbance of 0.08 at 220-241 nm and 0.05 at 241-350 nm) under radiation exposure conditions. This parameter control ensures minimal elution while maintaining filter functionality
Solution Approach 2:
The patent employs resin materials with specific properties (low elution rate, high radiation resistance) that combine filtering capability with resistance to radiation-induced elution, creating a composite solution that addresses both contamination and elution concerns
3Reliability
If the resin filter is subjected to strong radiation exposure for sterilization treatment, then aseptic properties are improved, but elution amount from the resin filter increases
Solution Approach 1:
The patent establishes specific parameter criteria for resin filters used in radiation sterilization, requiring the elution amount to maintain maximum absorbance of 0.08 at 220-241 nm and 0.05 at 241-350 nm even after radiation exposure. This parameter control ensures that strong sterilization treatment does not result in excessive elution
Solution Approach 2:
The patent employs a disposable resin filter that is designed to withstand radiation sterilization while maintaining minimal elution. The filter is discarded after use, ensuring that any potential elution does not affect the sample, thus maintaining reliability for single-use applications
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The resin filter effectively prevents the mixing of foreign fibers into samples, even under strong sterilization treatments, thereby enhancing the aseptic properties and reliability of the pipette in medical and biochemical applications.
Implementation Method 1
in a case where the resin filter is inserted into the connection portion and is subjected to radiation exposure such that an absorbed dose is 20 kGy or more
Implementation Method 2
the elution from the resin filter is suppressed to an extremely small amount
Data Source
AI summary
An object of the present invention is to provide a disposable pipette capable of avoiding mixing foreign matter into a sample. The disposable pipette of the present invention is a disposable pipette used in a medical field or a biochemical field, and includes a resin-made pipette main body having a connection portion connected to a suction device, and a resin filter inserted into the connection portion. In the resin filter, an elution amount, in a case where the resin filter is subjected to radiation exposure such that an absorbed dose is 20 kGy or more, is equivalent to a maximum absorbance of 0.08 or less in a wavelength range of 220 nm to 241 nm and is equivalent to a maximum absorbance of 0.05 or less in a wavelength range of 241 nm to 350 nm.