Pipette Tip Washing Manifold With UV Fiber Sterilization

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Solution Overview

Problem

Current methods for washing and sterilizing pipette tips in large-scale laboratory settings are inefficient and costly, leading to significant waste and contamination issues, as existing devices are either too expensive, complex, or not scalable for industrial use.

Innovation Solution

A washing device with a manifold dispenser system that directs fluid to multiple pipette tips using UV light and fiber optic channels for comprehensive cleaning and sterilization, combined with a UV curtain and agitatable platform for enhanced cleaning efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If plasma systems are used to clean pipette tips, then cleaning effectiveness is improved, but device cost and complexity increase significantly

Engineering Contradiction:
Improvecleaning effectivenessVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent replaces complex plasma generation systems with a simpler mechanical washing system using manifolds, spray nozzles, and rinse mechanisms that deliver cleaning solutions through pipette tips without requiring exotic plasma-generating equipment

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The invention adopts a cost-effective approach using disposable or easily replaceable washing components (manifolds, nozzles, tubing) that can be periodically replaced, avoiding the need for expensive, complex plasma systems while achieving adequate cleaning for reuse applications

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If complex cleaning systems with multiple jet streams are used, then cleaning capability is improved, but system complexity increases

Engineering Contradiction:
Improvecleaning capabilityVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The washing system is divided into separate functional modules: a manifold for fluid distribution, individual spray nozzles for each tip position, and a rinse mechanism, allowing each component to be simple while the combination provides comprehensive cleaning coverage

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The manifold and nozzle system is designed to handle multiple functions (washing, rinsing, drying) through a single integrated structure that can service multiple pipette tips simultaneously, reducing overall system complexity compared to individual cleaning stations for each tip

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Device complexity

If small-scale cleaning methods are used, then device simplicity is maintained, but cleaning scale is insufficient for large laboratories

Engineering Contradiction:
Improvedevice simplicityVSAvoidcleaning scale
Core Design Contradiction:
Device complexityVSProductivity

Solution Approach 1:

The system merges multiple cleaning functions (washing, rinsing, drying) and multiple tip processing capabilities into a single integrated device that can handle 96-tip racks, achieving large-scale laboratory productivity while maintaining operational simplicity through automated multi-step cycles

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system transitions from processing tips individually or in small groups to processing entire 96-tip racks simultaneously by adding the spatial dimension of parallel processing through the rack-compatible manifold design, dramatically increasing throughput without proportionally increasing complexity

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

4Reliability

If pipette tips are discarded after single use, then contamination risk is eliminated, but operational cost and waste increase significantly

Engineering Contradiction:
Improvecontamination preventionVSAvoidwaste
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The system recovers pipette tips for reuse through automated washing and sterilization cycles, eliminating the need to discard functional tips after single use while maintaining contamination prevention through thorough cleaning and sterilization processes that restore tips to safe reusability

Inventive Principle:
Principle #34Discarding and recovering

Solution Approach 2:

The cleaning process transforms the state of used pipette tips by changing physical parameters (temperature, chemical exposure, mechanical agitation) to remove contaminants and restore the tips to a clean, sterile state suitable for reuse, thereby converting waste material back into usable consumables

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution enables efficient and economical large-scale sterilization of pipette tips, reducing waste and contamination risks, while being cost-effective and adaptable for industrial-scale use.

Implementation Method 1

an ultra-violet (UV) light source, and a plurality of fiber optic channels coupled to the UV light source, each of the fiber optic channels extending into a corresponding one of the liquid outputs

Methodology Applied
Scientific EffectUltraviolet light: Light

Implementation Method 2

a plurality of fiber optic channels coupled to the UV light source, each of the fiber optic channels extending into a corresponding one of the liquid outputs

Methodology Applied
Scientific EffectOptical fiber transmission: Optical Fibre

Implementation Method 3

a manifold dispenser comprising at least one liquid input and a plurality of liquid outputs that operably direct fluid to contact a plurality of laboratory consumables

Methodology Applied
Scientific EffectFluid flow:

Data Source

PatentUS11737641B2Pipette tip washing device
Publication Date: 2023.08.29 GRENOVA INC
  • US11737641B2 patent drawing
  • US11737641B2 patent drawing
  • US11737641B2 patent drawing

AI summary

A washing device comprises a manifold dispenser comprising at least one liquid input and a plurality of liquid outputs that operably direct fluid to contact a plurality of laboratory consumables held by a rack in the washing device, an ultra-violet (UV) light source, and a plurality of fiber optic channels coupled to the UV light source, each of the fiber optic channels extending into a corresponding one of the liquid outputs. The plurality of liquid outputs may each comprise a nozzle having an opening into which a respective one of the plurality of fiber optic channels extends.