Drug Delivery Piston Rod Reset via Gravity and Screw Thread

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Solution Overview

Problem

Existing drug delivery devices, particularly pen-type injectors, face challenges in efficiently resetting the piston rod mechanism after a cartridge is emptied, requiring manual intervention and potential complexity in refilling and reinitialization.

Innovation Solution

A drug delivery device with a mechanism that allows for the guided movement and easy resetting of the piston rod to its initial position using gravitational force, facilitated by a screw thread system and a reset nut with a spiral spring, enabling smooth axial and rotational movement without the need for additional dedicated reset elements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If manual resetting of the piston rod is required after cartridge replacement, then the device can maintain simple structure, but the ease of operation deteriorates due to additional manual intervention steps

Engineering Contradiction:
Improvestructure simplicityVSAvoidrefilling and reinitialization ease
Core Design Contradiction:
Device complexityVSEase of operation

Solution Approach 1:

The piston rod automatically resets to its initial position through gravitational force when the cartridge is replaced, eliminating the need for manual resetting operations. The system serves itself by using the weight of the piston rod to drive the resetting mechanism without user intervention.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The resetting mechanism transforms the static piston rod position into a dynamic resetting process. When the cartridge is removed, the piston rod is freed to move dynamically under gravitational influence, rotating the drive sleeve and resetting the mechanism automatically.

Inventive Principle:
Principle #15Dynamics

2Ease of operation

If a dedicated reset element is added to facilitate piston rod resetting, then the ease of operation improves, but the device complexity increases

Engineering Contradiction:
Improveresetting easeVSAvoidmechanism complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The piston rod serves dual functions: it acts as both the drug delivery actuator and the resetting mechanism driver. The same piston rod that delivers medication also, through its weight and movement, automatically resets the drive mechanism when the cartridge is replaced, eliminating the need for a separate reset element.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The resetting function is merged with the existing piston rod and drive sleeve mechanism. The piston rod's axial movement is coupled with rotational movement of the drive sleeve through gravitational force, combining delivery and resetting functions into a unified mechanical system.

Inventive Principle:
Principle #5Merging (Combining)

3Ease of operation

If the piston rod is allowed to move freely for resetting, then the ease of operation improves, but mechanical stress on components increases

Engineering Contradiction:
Improveresetting smoothnessVSAvoidmechanical stress on components
Core Design Contradiction:
Ease of operationVSStress or pressure

Solution Approach 1:

The mechanism is designed to allow the piston rod to move under gravitational force along a controlled path. The drive sleeve and guiding means create a mechanical environment where the piston rod's weight is converted into useful resetting motion without creating excessive stress concentrations or uncontrolled movements.

Inventive Principle:
Principle #12Equipotentiality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables straightforward and efficient refilling and reinitialization of the device, reducing user complexity and mechanical stress on components, ensuring reliable and user-friendly operation for multiple dose administration.

Implementation Method 1

a reset nut with a spiral spring

Methodology Applied
Scientific EffectSpiral spring: Spring

Implementation Method 2

enabling a reset of the piston rod to a start position

Methodology Applied
Scientific EffectGravitational force: Gravitation

Data Source

PatentUS10398845B2Drug delivery device
Publication Date: 2019.09.03 SANOFI AVENTIS DEUT GMBH
  • US10398845B2 patent drawing
  • US10398845B2 patent drawing
  • US10398845B2 patent drawing

AI summary

A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated.