Pixel-Level Spectral Filtering for Non-Invasive Glucose Sensing
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Solution Overview
Problem
Existing methods for blood glucose testing in diabetes are invasive, painful, and require complex equipment, limiting real-time monitoring and increasing infection risk, while existing non-invasive methods are bulky and expensive.
Innovation Solution
A system for analyte spectral collection using a shell with an imaging spectrum detection apparatus and periodic pixel-level light filtering structure, integrated into a portable device, performs spectral modulation to obtain spectral data from the skin without invasive electrochemical reactions, utilizing fluorescence spectroscopy for non-invasive testing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If traditional invasive testing methods (venous blood test or fingerstick blood test) are used, then testing accuracy is ensured, but patient comfort deteriorates and infection risk increases
Solution Approach 1:
The patent replaces the mechanical invasive testing system (needles, lancets, blood collection tubes) with an optical detection system that uses light to measure glucose concentration through skin tissue. The optical system includes light sources emitting at multiple wavelengths, detectors that measure light absorption or scattering, and processing units that calculate glucose levels from the optical signals, thereby eliminating physical penetration of the skin barrier.
Solution Approach 2:
The patent introduces skin tissue as an intermediary medium between the testing system and the blood glucose. Instead of directly accessing blood, the system shines light through the skin, which acts as a medium that allows optical detection of glucose molecules in underlying blood vessels. This intermediary approach enables indirect measurement without breaking the skin barrier.
2Object-affected harmful factors
If existing non-invasive testing methods are used, then patient comfort is improved, but device complexity and cost increase
Solution Approach 1:
The patent segments the optical detection system into multiple independent wavelength channels, each targeting specific glucose absorption peaks. By dividing the spectrum into discrete wavelength bands (e.g., 800-1000nm, 1000-1200nm, 1200-1400nm), the system can use simpler detectors for each band rather than requiring a single complex broadband detector, thereby reducing overall system complexity while maintaining non-invasive operation.
Solution Approach 2:
The patent changes the operational parameters of the light sources to emit at specific wavelengths corresponding to glucose absorption peaks. By tuning the light sources to fixed, optimized wavelengths rather than using broadband illumination, the system simplifies the detection requirements and reduces the complexity of spectral analysis algorithms, making the non-invasive device more practical and cost-effective.
3Object-affected harmful factors
If existing non-invasive testing methods are used, then patient comfort is improved, but real-time monitoring capability deteriorates
Solution Approach 1:
The patent implements continuous illumination of the skin tissue with multiple wavelength light sources, allowing for uninterrupted optical measurements. The system continuously detects changes in light absorption as glucose levels fluctuate, enabling real-time monitoring. The continuous operation of the optical path without mechanical intervention or sample preparation delays ensures that glucose concentration changes are captured immediately as they occur in the bloodstream.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables simple, low-cost, and real-time non-invasive testing of blood glucose by analyzing uneven spectral distributions, providing accurate glucose concentration measurements without piercing the skin, improving patient comfort and convenience.
Implementation Method 1
the periodic pixel-level light filtering structure performs spectral modulation on an incoming light signal
Implementation Method 2
the imaging spectrum detection apparatus obtains a light signal from the imaging area, the imaging spectrum detection apparatus includes a sensor
Implementation Method 3
utilizing fluorescence spectroscopy for non-invasive testing
Implementation Method 4
The light filtering image element channels with pixel-level light filtering structures of different shapes correspond to different spectral filter coefficients
Data Source
AI summary
The present invention provides a system for analyte spectral collection and a system for testing an analyte, and the system for analyte spectral collection, which relate to the field of optical analysis. The system for analyte spectral collection includes a shell and an imaging spectrum detection apparatus. The apparatus obtains a light signal in an imaging area, and includes a sensor and a periodic pixel-level light filtering structure, disposed on a surface of the sensor. The filtering structure performs spectral modulation on an incoming light signal, and the sensor generates an image containing spectral information to be tested. In this application, the periodic pixel-level light filtering structure disposed on the surface of the sensor performs spectral modulation on the incoming light signal, so that the sensor generates an image containing spectral information to be tested, helping analyte spectral collection be performed more simply.