Plant-Based Growth Factor Cosmetic Formulation
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Solution Overview
Problem
Human-derived growth factors used in cosmetic compositions often cause side effects such as unwanted hair growth, tumors, and skin health concerns due to their large molecule size, unpleasant scent, and controversial sourcing, limiting their effectiveness and safety for skin care applications.
Innovation Solution
A topical composition incorporating plant-based growth factors, such as synthetic human epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), transforming growth factor (TGF), or insulin growth factor (IGF), combined with peptides like acetyl hexapeptide-8 and antioxidants like ubiquinone, to improve skin appearance and health without the drawbacks of human-derived factors.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If human-derived growth factors are used in cosmetic compositions, then skin repair and collagen formation benefits are achieved, but side effects such as unwanted hair growth, tumors, and skin health concerns occur
Solution Approach 1:
The patent uses plant-based growth factors that replicate the functional properties of human growth factors without using actual human tissue. The plant-based EGF, VEGF, TGF, and IGF provide similar skin repair and collagen formation benefits while eliminating the harmful side effects associated with human-derived sources, including unwanted hair growth and tumor risks
Solution Approach 2:
The patent introduces plant-based growth factors as an intermediary substance that mediates between the desired skin repair benefits and the harmful effects of human-derived growth factors. These plant-based factors serve as a safe alternative that delivers the therapeutic effects without the associated risks
2Strength
If human growth factors are used to promote collagen and elastin formation, then skin firmness and elasticity are improved, but the large molecule size prevents penetration through intact skin
Solution Approach 1:
The patent modifies the molecular parameters of growth factors by using plant-based versions that may have different molecular weights and structures compared to human-derived factors. This parameter change enables better penetration through the skin barrier while maintaining the ability to stimulate collagen and elastin formation for improved skin firmness
3Duration of action of stationary object
If human growth factors are used continuously, then skin repair effects are maintained, but skin health concerns and unpleasant scent arise
Solution Approach 1:
The patent employs plant-based growth factors that can be used continuously without the skin health concerns associated with prolonged use of human-derived factors. The plant-based sources do not carry the same risk of skin reactions, allergies, or other health concerns that limit continuous use of human growth factors
4Reliability
If human-derived growth factors are used, then growth factor benefits are achieved, but controversial sourcing and unpleasant scent are problems
Solution Approach 1:
The patent uses plant-based growth factors that replicate the beneficial properties of human growth factors without the ethical controversies surrounding human tissue sourcing. The plant-based sources provide a clear, ethically sound supply chain while maintaining the ability to produce effective growth factor formulations
Data Source
AI summary
Disclosed in certain embodiments herein is a formulation including a plant-based growth factor and at least one of a peptide, an antioxidant and a botanical agent. The formulation has been found to improve the properties of the skin on the face and on areas under the eye. Also disclosed herein are methods of administering the formulation described herein for treating a skin.