Plant-Derived Active Ingredient Using Vegetable Oil Extraction

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Solution Overview

Problem

Current cosmetic and pharmaceutical applications face limitations in effectively utilizing plant extracts due to challenges in extraction methods and stability, particularly with the use of solvents that pose health or environmental risks, and the need for enhanced bioactive compound delivery for skin health benefits like collagen synthesis.

Innovation Solution

A plant-derived active ingredient combining extracts from Olea, Tilia, and Cydonia plants, utilizing vegetable oils as green solvents for extraction and formulation, which allows for high polyphenol concentration and stability, and includes a method involving microwave and ultrasonic treatment for enhanced bioavailability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If traditional solvent-based extraction methods are used, then bioactive compounds can be extracted, but health and environmental risks arise from toxic solvents

Engineering Contradiction:
Improvebioactive compound extractionVSAvoidhealth and environmental risks from toxic solvents
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The patent changes the extraction parameter from toxic chemical solvents to safe vegetable oils, transforming the extraction medium to eliminate harmful effects while maintaining extraction capability for bioactive compounds

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs food-grade vegetable oils that are safe, biodegradable, and environmentally friendly, replacing persistent toxic solvents with natural, renewable extraction media that pose no health or environmental risks

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If plant extracts are used for cosmetic applications, then skin health benefits are achieved, but stability and bioavailability of bioactive compounds are limited

Engineering Contradiction:
Improveskin health benefitsVSAvoidstability and bioavailability of bioactive compounds
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent uses vegetable oils as intermediary carriers that stabilize bioactive compounds from plant extracts, enhancing their bioavailability and stability while delivering skin health benefits through cosmetic applications

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates composite formulations combining vegetable oil-based extracts with active ingredients, forming stable compositions that maintain bioactivity and improve skin health outcomes

Inventive Principle:
Principle #40Composite materials

3Quantity of substance

If high polyphenol concentration is achieved, then antioxidant and anti-inflammatory effects are enhanced, but formulation stability becomes challenging

Engineering Contradiction:
Improvepolyphenol concentrationVSAvoidformulation stability
Core Design Contradiction:
Quantity of substanceVSStability of the object's composition

Solution Approach 1:

The patent changes the formulation parameters by using vegetable oils as the continuous phase, which stabilizes high polyphenol concentrations while maintaining antioxidant and anti-inflammatory effects

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution results in a stable, high-polyphenol formulation that effectively stimulates collagen synthesis in human skin explants, offering improved skin health benefits and overcoming the limitations of traditional extraction methods.

Implementation Method 1

utilizing vegetable oils as green solvents for extraction

Methodology Applied
Scientific EffectExtraction: Liquid-Liquid Extraction

Implementation Method 2

includes a method involving microwave and ultrasonic treatment for enhanced bioavailability

Methodology Applied
Scientific EffectMicrowave heating: Microwave Radiation

Implementation Method 3

includes a method involving microwave and ultrasonic treatment for enhanced bioavailability

Methodology Applied
Scientific EffectUltrasonic vibration: Ultrasonic Vibration

Data Source

PatentUS11684563B2Plant derived active ingredient comprising plant extracts
Publication Date: 2023.06.27 DONCAB
  • US11684563B2 patent drawing

AI summary

A plant derived active ingredient and a cosmetic and a drug composition including the plant derived ingredient including: an extract from at least one plant of the gender Olea, an extract from at least one plant of the gender Tilia and/or an extract from at least one plant of the gender Cydonia.