Plant Extract Composition Activating Caspase-14 Expression
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Solution Overview
Problem
Current cosmetic products do not effectively address the deficiency and degradation of caspase-14 expression in human skin, leading to visible signs of aging such as wrinkles, lines, sagging, hyperpigmentation, and age spots, despite their focus on chronological and photo-aging.
Innovation Solution
A cosmetic composition comprising specific plant extracts like litchi, glasswort, and other botanicals that activate caspase-14 expression in human skin, improving hydration characteristics, skin barrier strength, and protection against UV irradiation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional cosmetic products are used to treat signs of aging, then chronological and photo-aging symptoms are addressed, but caspase-14 deficiency and degradation are not effectively treated
Solution Approach 1:
The patent changes the biochemical parameter of caspase-14 enzyme activity in the skin by applying cosmetic compositions containing specific ingredients (such as plant extracts, vitamins, and other bioactive compounds) that stimulate caspase-14 expression and activity. This parameter change directly addresses the deficiency and degradation of caspase-14 associated with aging skin.
Solution Approach 2:
The patent uses cosmetic compositions as intermediaries that contain specific ingredients (e.g., plant extracts, vitamins A, C, E, and other bioactive compounds) which act as mediators to stimulate caspase-14 expression. These intermediaries bridge the gap between external application and internal skin enzyme activation.
2Reliability
If caspase-14 expression is activated through cosmetic composition, then skin hydration and barrier strength are improved, but the complexity of the composition increases
Solution Approach 1:
The cosmetic composition is designed to perform multiple functions simultaneously: stimulating caspase-14 expression, improving skin hydration, strengthening the skin barrier, and protecting against UV damage. This multi-functionality reduces the need for separate products and simplifies the overall skincare regimen while achieving comprehensive skin health benefits.
Solution Approach 2:
The patent combines multiple bioactive ingredients (plant extracts, vitamins, and other compounds) into a single cosmetic composition that works synergistically to activate caspase-14. This merging of ingredients creates a unified product that addresses multiple skin concerns through the common mechanism of caspase-14 activation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition enhances caspase-14 activity, improving skin hydration, strengthening the skin barrier, and preventing age spots by increasing caspase-14 expression, particularly in skin types with low activity levels, such as Japanese skin.
Implementation Method 1
A cosmetic composition comprising specific plant extracts like litchi, glasswort, and other botanicals that activate caspase-14 expression in human skin
Data Source
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AI summary
A method of cosmetic care comprising activating capsase-14 expression in skin deficient in caspase-14 expression by applying, on at least one skin zone in need thereof, an effective amount of a plant extract selected from the group consisting of litchi, glasswort, peach, soja seed, sweet basil, cucumber, chanterelle, leek, kiwi fruit, rhubarb, grapefruit, wheat, raspberry, plum, and mixtures thereof, to activate caspase-14 expression in said skin.