Plant Glycoprotein Microcapsules for Eco-Friendly Stabilization

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Solution Overview

Problem

Existing microcapsules lack ease of preparation and eco-friendliness, and do not effectively stabilize active ingredients with anti-oxidative properties, especially when using synthetic polymers or surfactants.

Innovation Solution

Microcapsules composed of a polysaccharide with a negative net charge, a protein with an isoelectric point of 4-6, and a plant-derived glycoprotein with negative net charge, which form stable particles reversibly depending on pH and provide anti-oxidative activity, eliminating the need for organic solvents during preparation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If synthetic polymers or surfactants are used to stabilize active ingredients, then stabilization effect is achieved, but environmental friendliness and ease of preparation deteriorate

Engineering Contradiction:
Improvestabilization effectVSAvoidease of preparation
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent utilizes pH changes to control the charge states of natural polymers, enabling them to self-assemble into stable microcapsules. By adjusting pH to specific ranges (e.g., pH 4-6 for protein isoelectric points), the system achieves stabilization without synthetic additives, resolving the contradiction between stabilization effectiveness and ease of eco-friendly preparation

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention combines multiple natural components (polysaccharides, proteins, and plant-derived glycoproteins) with complementary properties to create a composite microcapsule system. This composite approach achieves superior stabilization效果 while maintaining natural composition, eliminating the need for synthetic polymers or surfactants

Inventive Principle:
Principle #40Composite materials

2Reliability

If synthetic polymers are used for capsule preparation, then stabilization capability is improved, but environmental friendliness deteriorates

Engineering Contradiction:
Improvestabilization capabilityVSAvoidenvironmental friendliness
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent employs readily available natural materials (plants, fruits, vegetables) that are biodegradable and environmentally benign. These natural polymers serve as temporary, disposable stabilizing agents that decompose harmlessly in the environment, replacing persistent synthetic polymers while maintaining stabilization functionality

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

By utilizing pH-dependent charge interactions of natural polymers, the system achieves synthetic-free stabilization. The natural polymers self-assemble through electrostatic interactions at specific pH ranges, providing environmental-friendly stabilization without requiring synthetic additives

Inventive Principle:
Principle #35Parameter changes

3Ease of manufacture

If conventional capsule methods are used, then preparation simplicity is maintained, but anti-oxidative activity and material stability deteriorate

Engineering Contradiction:
Improvepreparation simplicityVSAvoidanti-oxidative activity
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent incorporates plant-derived glycoproteins with inherent anti-oxidative properties into the microcapsule composition. These glycoproteins work synergistically with polysaccharides and proteins to provide both structural stability and anti-oxidative protection, achieving dual functionality without complicating the preparation process

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The natural polymer components serve multiple functions simultaneously: polysaccharides provide structural framework, proteins offer stabilization through charge interactions, and plant glycoproteins contribute anti-oxidative activity. This multi-functionality maintains preparation simplicity while enhancing material protection

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

These microcapsules stabilize active ingredients effectively, prevent oxidation and decomposition, and are more environmentally friendly, forming soft hydrogel microcapsules that can be used as pH-sensitive carriers without causing irritation.

Implementation Method 1

the microcapsules according to the embodiments of the present invention are characterized in that they form or disintegrate stable particles reversibly depending on pH, and thus can be used as a pH-sensitive carrier

Methodology Applied
Scientific EffectpH-sensitive carrier behavior:

Implementation Method 2

it is thought that when glycoproteins originated from plant peptides have anti-oxidative activity, it is possible to protect a material carried by capsules more stably

Methodology Applied
Scientific Effectanti-oxidative activity:

Data Source

PatentUS9802064B2Microcapsule comprising glycoprotein derived from plants
Publication Date: 2017.10.31 AMOREPACIFIC CORP
  • US9802064B2 patent drawing
  • US9802064B2 patent drawing
  • US9802064B2 patent drawing

AI summary

The present invention relates to a microcapsule containing a glycoprotein derived from plants. Also, the present invention provides a microcapsule having oxidation ability and which is easy to prepare. Through said antioxidant capacity, oxidation and decomposition of an internally contained material can be prevented. According to the microcapsule of the present invention, the active components, in a form which was previously stabilized by a synthetic polymer derived from crude oil or by a surfactant, can be stabilized by naturally derived components. Also, since an organic solvent is not additionally used during the capsule preparation process, the preparation is simple and eco-friendly.