Plant-Derived Immune Compositions for Rapid Cellular Response
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Solution Overview
Problem
Existing immune systems in mammals, particularly newborns, struggle to mount a rapid and effective secondary immune response to pathogens due to underdeveloped immune maturity, and conventional transfer factors derived from animal sources are not suitable for individuals with dietary restrictions or preferences.
Innovation Solution
Development of plant-based compositions containing processed plant products, such as seed extracts from radishes and mustard greens, which include proteins like defensins and cruciferins, to modulate cell-mediated immunity and elicit a rapid immune response.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional animal-derived transfer factors are used to modulate cellular immunity, then immune response efficacy is improved, but suitability for individuals with dietary restrictions deteriorates
Solution Approach 1:
The patent creates plant-based compositions that copy and replicate the immune-modulating functions of animal-derived transfer factors. The plant compositions contain proteins and bioactive compounds that mimic the cellular immunity modulation effects of bovine colostrum, providing a vegetarian alternative with comparable efficacy.
Solution Approach 2:
The patent changes the source parameter from animal-derived to plant-derived materials while maintaining the functional output. By identifying and isolating specific plant proteins and bioactive compounds that can modulate cellular immunity, the patent transforms the composition source without sacrificing the desired immune response effects.
2Adaptability or versatility
If plant-based compositions are developed as alternatives to animal-derived transfer factors, then suitability for dietary restrictions is improved, but immune response efficacy may deteriorate
Solution Approach 1:
The patent uses composite plant-based materials containing multiple proteins and bioactive compounds (such as defensins, cruciferins, and other immune-modulating substances) working together to achieve immune response efficacy comparable to animal-derived transfer factors. The composite nature of the plant composition allows for synergistic effects that compensate for the absence of animal-derived components.
3Object-affected harmful factors
If newborns with underdeveloped immune systems are targeted, then vulnerability to pathogens is improved, but ability to mount rapid secondary immune response deteriorates
Solution Approach 1:
The patent applies preliminary action by providing plant-based compositions to newborns that pre-condition the immune system. The compositions contain bioactive compounds that stimulate and accelerate the development of cellular immunity, enabling newborns to mount faster secondary immune responses before their immune systems are fully mature.
Data Source
AI summary
A composition that modulates cellular immunity in animals includes an ingredient derived from a plant. Such an ingredient may be referred to as “plant-derived” or “plant-based.” The plant-derived ingredient modulates cellular immunity in animals. Such a plant-derived ingredient may include an extract, fraction, or isolate from a seed of a plant, such as a seed of a plant from the family Brassicaceae. A method for modulating cellular immunity in an animal includes administering a plant-derived composition to the animal in amount that will cause the animal to elicit a cell-mediated immune response.