Low-Temperature Plasma Probe for Cartilage Ablation

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Solution Overview

Problem

Existing medical instruments fail to smoothly ablate cartilage surfaces without causing thermal damage, as prior art RF and laser devices are not capable of providing smooth surfaces and often result in unacceptable thermal damage to cartilage tissue.

Innovation Solution

A probe with an electrosurgical working end that generates a low-temperature plasma at two different surface locations, with specific ablation parameters, to ablate tissue while maintaining the cartilage surface integrity by controlling the plasma generation and temperature.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If prior art RF and laser devices are used to ablate cartilage, then tissue removal is achieved, but thermal damage is caused to cartilage tissue and smooth surfaces cannot be provided

Engineering Contradiction:
Improvesurface smoothnessVSAvoidthermal damage
Core Design Contradiction:
Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by transitioning from thermal energy delivery (RF and laser) to mechanical energy delivery through vibration. The electrosurgical instrument operates at frequencies between 20-100 kHz, causing cavitation and mechanical disruption of cartilage without significant thermal effects. This fundamental parameter change in energy type and frequency range enables smooth surface ablation while avoiding the thermal damage inherent in prior art RF and laser devices.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the thermal field (RF and laser energy) with a mechanical field (vibration and cavitation). By using piezoelectric or magnetostrictive elements to generate high-frequency vibrations in a fluid medium, the system creates cavitation bubbles that mechanically disrupt cartilage tissue. This substitution of energy modality eliminates thermal damage while achieving the desired ablation and surface smoothing.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Productivity

If high temperature plasma is used for ablation, then rapid tissue removal is achieved, but thermal damage is caused to surrounding tissue

Engineering Contradiction:
Improveablation rateVSAvoidthermal damage
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces thermal plasma ablation with mechanical cavitation ablation. Instead of using high-temperature plasma to vaporize tissue, the system uses high-frequency vibrations (20-100 kHz) to generate cavitation bubbles in the fluid medium. These bubbles collapse mechanically, disrupting cartilage tissue through physical force rather than thermal energy, thereby achieving rapid ablation without thermal damage to surrounding tissue.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent exploits phase transitions of the fluid medium (liquid to gas and back to liquid) to achieve mechanical ablation. High-frequency vibrations cause the fluid to undergo rapid phase changes, forming and collapsing cavitation bubbles. This phase transition mechanism converts thermal energy input into mechanical energy, enabling rapid tissue disruption through bubble collapse rather than direct thermal heating.

Inventive Principle:
Principle #36Phase transitions

3Reliability

If RF energy is applied to cartilage, then tissue ablation is achieved, but unacceptable thermal damage occurs to cartilage surface layers

Engineering Contradiction:
Improvecartilage surface integrityVSAvoidthermal damage
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent substitutes mechanical vibration and cavitation for RF thermal energy delivery. By using piezoelectric or magnetostrictive elements to generate high-frequency mechanical oscillations in the fluid medium, the system creates cavitation that mechanically removes damaged cartilage while preserving the surface layers. This mechanical approach eliminates the thermal diffusion that causes damage to surrounding healthy tissue in RF ablation.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent segments the energy delivery mechanism into localized cavitation events rather than continuous thermal heating. Each cavitation bubble forms and collapses independently, creating localized mechanical disruption only at the treatment site. This segmentation of energy action prevents thermal diffusion to surrounding tissue while effectively abling damaged cartilage and preserving surface integrity.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively smooths fibrillated cartilage surfaces without thermal damage, as demonstrated by tests showing no significant chondrocyte death and a smooth cartilage surface post-treatment, unlike prior art devices which caused substantial cell death.

Implementation Method 1

An electrosurgical working end is provided which generates a plasma at two different surface locations

Methodology Applied
Scientific EffectPlasma generation: Plasma

Implementation Method 2

The plasma at the gap will have a low temperature of 80° C. or below and the plasma at the opening will have a high temperature of 100° C. or above

Methodology Applied
Scientific EffectElectrosurgical ablation: Ablation

Data Source

PatentUS11672586B2Medical ablation system and method of use
Publication Date: 2023.06.13 RELIGN CORP
  • US11672586B2 patent drawing
  • US11672586B2 patent drawing
  • US11672586B2 patent drawing

AI summary

A probe for ablating tissue comprises an electrosurgical working end configured to provide a first plasma about a first surface location and a second plasma about a second surface location, the first plasma having first ablation parameters and the second plasma having second ablation parameters. The probe has a working end with a thickness below 3 mm and produces a low temperature plasma.