Automated Plasma Sample Transfer With RFID Traceability

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Solution Overview

Problem

The manual process of taking plasma samples from collection containers is prone to errors, including the risk of mixing samples from different containers, which can lead to contamination and incorrect identification of donor samples.

Innovation Solution

A device that automatically transfers liquid samples from collection containers to vacuum containers using a robot with pincer terminals, accompanied by a labelling system to ensure sample traceability, utilizing conveyor belts or other automated feeding methods and RFID labels for accurate identification.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual sample taking is performed, then operational flexibility is maintained, but sample mixing errors and contamination risks increase

Engineering Contradiction:
Improvesample identification accuracyVSAvoidmanual handling complexity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The system uses RFID tags and automated reading mechanisms where the containers themselves carry their identification information. The automated device reads the RFID tags and performs sample transfer without human intervention, making the system self-sufficient and eliminating manual handling errors.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces manual mechanical handling with an automated robotic system that uses RFID electromagnetic fields for identification. The robotic arm with cannula automatically transfers samples based on RFID-identified container sequences, substituting human mechanical operations with automated electromechanical systems.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If automated sample taking is implemented, then sample mixing errors are reduced, but device complexity increases

Engineering Contradiction:
Improvesample traceabilityVSAvoidautomation system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The automated device performs multiple functions: it reads RFID tags for identification, sequences containers based on donor information, transfers samples using robotic arm and cannula, and maintains traceability all in one integrated system. This multi-functionality reduces the need for separate systems and minimizes overall complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The RFID tag acts as an intermediary that carries identification information between the container and the reading device. This intermediary enables automated identification and tracking without requiring complex direct communication systems between the robotic arm and container labels.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Productivity

If manual handling is used, then equipment cost is lower, but handling time and contamination risk increase

Engineering Contradiction:
Improvesample processing speedVSAvoidcontamination risk
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The vacuum containers automatically draw plasma samples through the cannula using their own vacuum pressure, eliminating the need for external pumping equipment. This self-service mechanism reduces equipment complexity and cost while maintaining automated processing speed and minimizing contamination risks through closed-system transfer.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system uses vacuum pressure (pneumatic principle) to drive the plasma sample from the collection container through the cannula into the vacuum container. This pneumatic mechanism enables automated sample transfer without mechanical pumps or complex fluid control systems, reducing equipment cost while maintaining high processing speed and low contamination risk.

Inventive Principle:
Principle #29Pneumatics and hydraulics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device ensures sample traceability, reduces handling time, and minimizes the risk of contamination by automating the sample collection and labelling process, ensuring that samples are correctly identified and matched to their corresponding donor containers.

Implementation Method 1

a vacuum container (4) or vacuum tube, into which the sample of liquid will be automatically deposited

Methodology Applied
Scientific EffectVacuum: Vacuum

Data Source

PatentEP2209007B1Method for performing automatic taking of samples of liquid from collection containers
Publication Date: 2023.09.13 GRIFOLS
  • EP2209007B1 patent drawingFigure 1
  • EP2209007B1 patent drawingFigure 2
  • EP2209007B1 patent drawingFigure 3

AI summary

Device for taking samples of liquid from a collection container, characterised in that it comprises a support for liquid sample collection containers; a support for a set of containers into which the sample of liquid will be deposited; a support for connection elements; a container handling mechanism; and a device for inserting the containers into which the sample of liquid will be deposited into the connection element.