Plasma Tissue Ablation via Capacitive Coupling

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Solution Overview

Problem

Existing electrosurgical devices for tissue ablation face challenges such as slow treatment times, incomplete treatments, non-uniform ablation depths, and risk of injury to adjacent organs due to inefficiencies in delivering radiofrequency energy.

Innovation Solution

The use of a radiofrequency energy delivery system that ionizes an electrically non-conductive gas to form a plasma, which is then capacitively coupled through a thin dielectric wall to the tissue, allowing for uniform and controlled ablation depths with reduced risk to adjacent organs.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If traditional solid electrodes or balloon electrodes are used for radiofrequency ablation, then tissue ablation can be achieved, but treatment time is prolonged and ablation depth is non-uniform

Engineering Contradiction:
Improvetreatment speedVSAvoidablation depth uniformity
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The invention changes the physical state of the medium from solid (traditional electrodes) to gas (ionizable gas), and utilizes the transition to plasma state to achieve uniform energy distribution. The gas can penetrate tissue more evenly and the plasma formation provides consistent capacitive coupling across the tissue surface, resulting in uniform ablation depth and faster treatment time.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention introduces an ionizable gas as an intermediary medium between the electrode and the tissue. This gas serves as a mediator that enables more efficient and uniform energy transfer to the tissue through capacitive coupling when ionized, solving the problems of non-uniform ablation and prolonged treatment time associated with direct solid electrode contact.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If high power radiofrequency energy is delivered to achieve complete ablation, then treatment completeness improves, but risk of injury to adjacent organs increases

Engineering Contradiction:
Improveablation completenessVSAvoidrisk to adjacent organs
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The ionizable gas allows for localized energy delivery precisely where needed. The gas can be confined to the treatment area and only ionizes where radiofrequency energy is applied, providing complete ablation of the target tissue while limiting thermal spread to adjacent organs. The gas acts as a contained medium that directs energy locally rather than allowing uncontrolled thermal diffusion.

Inventive Principle:
Principle #3Local quality

3Productivity

If traditional electrode designs are used, then device simplicity is maintained, but treatment efficiency is reduced

Engineering Contradiction:
Improvetreatment efficiencyVSAvoiddevice structure
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The invention employs a gas-based system (pneumatic principle) instead of solid electrodes. The ionizable gas can be delivered through catheters or applicators in gaseous form, and its ability to be ionized provides enhanced treatment efficiency. The gas delivery system is relatively simple compared to complex solid electrode arrays, achieving better treatment efficiency without proportionally increasing device complexity.

Inventive Principle:
Principle #29Pneumatics and hydraulics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method enables rapid, uniform tissue ablation with controlled depth and reduced risk to adjacent tissues by effectively delivering radiofrequency energy through a plasma formed in an electrically non-conductive gas, improving treatment efficiency and safety.

Implementation Method 1

The gas is ionized to form a plasma, typically by application of a high voltage radiofrequency voltage

Methodology Applied
Scientific EffectIonization: Ionisation

Implementation Method 2

the first dielectric becomes ionized, typically forming a gas plasma, and the second dielectric allows current flow to the tissue via capacitive coupling

Methodology Applied
Scientific EffectCapacitive coupling: Capacitance

Implementation Method 3

delivering radiofrequency energy to the surface... the second dielectric allows current flow to the tissue via capacitive coupling

Methodology Applied
Scientific EffectDielectric heating: Dielectric Heating

Data Source

PatentUS10213246B2Tissue ablation systems and method
Publication Date: 2019.02.26 AXORA MEDICAL INC
  • US10213246B2 patent drawing
  • US10213246B2 patent drawing
  • US10213246B2 patent drawing

AI summary

Tissue is treated using a radiofrequency power supply connected to an applicator having a chamber filled with an electrically non-conductive gas surrounded by a thin dielectric wall. A radiofrequency voltage is applied at a level sufficient to ionize the gas into a plasma and to capacitively couple the ionized plasma with the tissue to deliver radiofrequency current to ablate or otherwise treat the tissue.