Disinfecting wound dressing and process for preparing such

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Solution Overview

Problem

Current wound dressings for burn wounds are complex, prone to sticking, lead to wound trauma, and quickly saturate, necessitating frequent changes, which can cause discomfort and increase infection risk, with no effective solution for sustained antimicrobial protection without environmental concerns.

Innovation Solution

A yarn-based wound dressing with a plasma-treated antimicrobial coating that prevents microbial growth, absorbs and evaporates exudate efficiently, and does not stick to creams or ointments, allowing prolonged use without reapplication, using a multi-layer structure with a non-stick contact layer, absorbing layer, evaporation layer, and antimicrobial top layer.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If silver is used as antimicrobial agent in wound dressing, then antimicrobial activity is improved, but adhesion to wound bed increases causing wound trauma

Engineering Contradiction:
Improveantimicrobial activityVSAvoidwound trauma
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical form of silver from ionic silver (silver nitrate) to organic silver compounds (silver sulfadiazine, silver metronidazole, silver ceftriaxone). This parameter change maintains antimicrobial activity while eliminating the adhesion problem that causes wound trauma, as the organic silver compounds do not form adherent precipitates on the wound bed.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent combines silver compounds with organic substances (sulfadiazine, metronidazole, ceftriaxone) to create composite antimicrobial agents. These composite materials provide sustained antimicrobial protection without the adverse adhesion effects of pure ionic silver, resolving the contradiction between effectiveness and tissue damage.

Inventive Principle:
Principle #40Composite materials

2Quantity of substance

If wound dressing absorbs exudate quickly, then saturation occurs faster requiring frequent changes, but if it absorbs slowly then infection risk increases

Engineering Contradiction:
Improveexudate absorption capacityVSAvoiddressing change frequency
Core Design Contradiction:
Quantity of substanceVSLoss of time

Solution Approach 1:

The patent modifies the absorption parameters of the dressing by incorporating hydrocolloid particles with controlled porosity and composition. These particles absorb exudate at an optimized rate that prevents both rapid saturation and infection risk, allowing the dressing to maintain protective function for extended periods without frequent changes.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses hydrocolloid particles with controlled porous structure to manage exudate absorption. The porous material provides optimal capillary action that absorbs exudate gradually and maintains a balanced moisture environment, preventing both over-saturation and insufficient protection against infection.

Inventive Principle:
Principle #31Porous materials

3Reliability

If antimicrobial compounds are physically incorporated in fibre bulk, then short term efficacy is achieved, but long term protection is limited and environmental contamination occurs

Engineering Contradiction:
Improveantimicrobial efficacyVSAvoidduration of protection
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent merges multiple antimicrobial mechanisms into a single integrated system: organic silver compounds provide sustained release, hydrocolloid particles provide contact killing, and the polymeric matrix provides structural support. This combination achieves both short-term and long-term antimicrobial protection while preventing environmental contamination through controlled release mechanisms.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates a composite wound dressing incorporating organic silver compounds, hydrocolloid particles, and polymeric materials. This composite structure provides sustained antimicrobial protection over extended periods while controlling the release of antimicrobial agents to prevent environmental contamination, resolving the contradiction between efficacy duration and environmental safety.

Inventive Principle:
Principle #40Composite materials

4Reliability

If complex wound dressing structure is used, then protection against infection is improved, but application complexity increases requiring skilled personnel

Engineering Contradiction:
Improveinfection protectionVSAvoidapplication complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges multiple protective functions (antimicrobial action, exudate absorption, wound bed protection, infection barrier) into a single integrated dressing layer. This unified structure provides comprehensive infection protection while simplifying application to a single step, eliminating the need for multiple separate applications and reducing the skill level required for proper application.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The dressing effectively prevents microbial colonization, reduces wound trauma, minimizes moisture leakage, and can be used for several days, reducing patient discomfort, medical workload, and mortality rates while avoiding environmental antimicrobial contamination.

Implementation Method 1

providing biocidal features to the substrate surface by exposing the substrate surface to an antimicrobial active compound reaction

Methodology Applied
Scientific EffectPlasma treatment: Plasma

Implementation Method 2

absorbing layer, evaporation layer and top layer

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Implementation Method 3

does not allow sufficient evaporation of water content from the exudate

Methodology Applied
Scientific EffectEvaporation: Evaporation

Data Source

PatentUS9883974B2Disinfecting wound dressing and process for preparing such
Publication Date: 2018.02.06 NEDERLANDSE ORG VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO
  • US9883974B2 patent drawing
  • US9883974B2 patent drawing
  • US9883974B2 patent drawing

AI summary

A process for preparing a disinfecting wound dressing for the protection of wounds, such as burn wounds, ulcers and cuts, the process comprising the steps of providing a yarn-based substrate, subjecting a surface of the substrate to a plasma environment, thereby providing non-leaching and biocidal features to the substrate surface by exposing the substrate surface to an antimicrobial active compound reaction.