Plethysmographic Respiration Rate Detection via Waveform Analysis

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Solution Overview

Problem

Conventional pulse oximetry systems face errors due to venous blood movement during patient motion and fail in conditions of low perfusion, intense light, and electrosurgical interference, leading to inaccuracies in measuring arterial oxygen saturation and pulse rate.

Innovation Solution

A plethysmographic respiration processor is developed to provide accurate respiration rate readings by processing optical properties of pulsatile blood flow, combining with other sensors like microphones or acoustic monitors to enhance accuracy and robustness, using a preprocessor, processors, and decision logic to derive respiration rate from plethysmograph waveforms.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional pulse oximetry is used to measure arterial oxygen saturation and pulse rate, then the measurement can be obtained under normal conditions, but the measurement accuracy deteriorates during patient motion due to venous blood movement

Engineering Contradiction:
Improvemeasurement accuracyVSAvoidmeasurement reliability under motion
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent segments the pulsatile blood flow signal into arterial and venous components by analyzing different frequency bands and waveform characteristics. The processor separates the arterial pulse signal (higher frequency) from venous contamination (lower frequency) to accurately measure arterial oxygen saturation and pulse rate even during patient motion.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system uses feedback mechanisms where the processed venous blood signal is analyzed and used to adjust the arterial oxygen saturation measurement. The processor continuously monitors the plethysmograph waveform and adjusts the measurement algorithm based on detected motion artifacts, improving reliability under motion conditions.

Inventive Principle:
Principle #23Feedback

2Measurement precision

If conventional pulse oximetry is used under conditions of low perfusion, intense ambient light, or electrosurgical interference, then the system structure remains simple, but the measurement accuracy deteriorates in these challenging scenarios

Engineering Contradiction:
Improvemeasurement accuracyVSAvoidsensitivity to low perfusion, light interference, and electrosurgical interference
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent converts harmful factors into beneficial signals by using the plethysmograph waveform's amplitude and shape information, which are affected by low perfusion and motion, as additional parameters for respiratory rate detection. The system processes these previously harmful variations to extract respiratory information, turning measurement challenges into detection opportunities.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The system changes measurement parameters by analyzing multiple characteristics of the plethysmograph waveform including amplitude modulation, frequency shifts, and shape changes. By monitoring multiple parameters simultaneously (pleth amplitude, pleth frequency, waveform morphology), the system maintains accuracy under varying conditions of perfusion, light interference, and electrosurgical exposure.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If advanced pulse oximetry processes the venous blood signal to report true arterial oxygen saturation and pulse rate under motion conditions, then measurement accuracy under motion improves, but the device complexity increases

Engineering Contradiction:
Improvearterial oxygen saturation and pulse rate accuracy under motionVSAvoidsignal processing complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent implements a universal processor that handles multiple functions: arterial oxygen saturation measurement, pulse rate detection, and respiratory rate monitoring. The same signal processing algorithms used to separate arterial from venous signals are also applied to extract respiratory information, reducing overall system complexity while maintaining accuracy across multiple parameters.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system merges the arterial oxygen saturation measurement function with respiratory rate detection by using the same plethysmograph waveform processing pipeline. The processor combines analysis of pulse amplitude variations, frequency modulations, and waveform shapes to simultaneously determine both arterial saturation and respiratory rate, reducing computational overhead and device complexity.

Inventive Principle:
Principle #5Merging (Combining)

4Measurement precision

If plethysmographic respiration processing is added to provide accurate respiration rate readings, then respiration measurement accuracy improves under challenging conditions, but the device complexity increases

Engineering Contradiction:
Improverespiration rate accuracyVSAvoidprocessor complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent implements dynamic processing where the system adapts its analysis based on signal quality and detected conditions. The processor dynamically adjusts which waveform characteristics to analyze (amplitude, frequency, shape) depending on the prevailing conditions such as perfusion level, motion intensity, and ambient light, optimizing respiratory rate accuracy without requiring complex fixed algorithms for all scenarios.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively improves the accuracy and robustness of respiration rate measurements, even under challenging conditions, by isolating respiratory-induced effects on blood volume and waveform intensity, providing a reliable measure that can be used alone or in conjunction with other monitoring methods.

Implementation Method 1

A typical pulse oximetry system utilizes an optical sensor clipped onto a fingertip to measure the relative volume of oxygenated hemoglobin in pulsatile arterial blood flowing within the fingertip

Methodology Applied
Scientific EffectOptical absorption: Absorption (EM radiation)

Data Source

PatentUS20220400962A1Plethysmographic respiration rate detection
Publication Date: 2022.12.22 MASIMO CORP
  • US20220400962A1 patent drawing
  • US20220400962A1 patent drawing
  • US20220400962A1 patent drawing

AI summary

A plethysmographic respiration processor is responsive to respiratory effects appearing on a blood volume waveform and the corresponding detected intensity waveform measured with an optical sensor at a blood perfused peripheral tissue site so as to provide a measurement of respiration rate. A preprocessor identifies a windowed pleth corresponding to a physiologically acceptable series of plethysmograph waveform pulses. Multiple processors derive different parameters responsive to particular respiratory effects on the windowed pleth. Decision logic determines a respiration rate based upon at least a portion of these parameters.