Pneumonia Readmission Prediction Using Ensemble Machine Learning

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Solution Overview

Problem

Current tools for predicting pneumonia readmission lack accuracy due to their simplistic approaches that do not consider patient history or a holistic view of the patient's condition, and they rely on information available only after discharge, limiting the ability to reduce readmission risk during discharge planning.

Innovation Solution

An ensemble of machine learning models is applied to patient information available prior to discharge, using severity metrics and other patient data to predict readmission risk, allowing for timely interventions such as modifying discharge protocols, ordering additional testing, and scheduling follow-up appointments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If existing prediction tools use simple rubrics that do not consider patient history, then the tools are easier to operate, but the prediction accuracy deteriorates

Engineering Contradiction:
Improveease of use of prediction toolVSAvoidprediction accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The prediction system segments patient information into multiple distinct features including demographic features, clinical features, laboratory features, and medication features. Each segment is processed and weighted independently by the machine learning model, allowing comprehensive analysis while maintaining systematic organization of complex data

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system combines multiple types of patient information (demographics, clinical data, lab results, medication history) into a composite prediction model. This composite approach integrates diverse data sources to create a holistic view of patient risk, improving prediction accuracy beyond simple rubrics

Inventive Principle:
Principle #40Composite materials

2Loss of information

If prediction tools rely on information available only after discharge, then the information completeness improves, but the ability to intervene during discharge planning deteriorates

Engineering Contradiction:
Improveinformation completenessVSAvoidtiming for intervention
Core Design Contradiction:
Loss of informationVSLoss of time

Solution Approach 1:

The system performs prediction actions preliminarily, during the discharge planning phase rather than after discharge. By calculating readmission risk using available pre-discharge information, the system enables timely interventions such as modifying discharge instructions, arranging follow-up care, or adjusting medication plans before the patient leaves the hospital

Inventive Principle:
Principle #10Preliminary action

3Device complexity

If simple rubrics are used to determine pneumonia severity, then the decision-making process is simplified, but the ability to predict readmission deteriorates

Engineering Contradiction:
Improvecomplexity of assessment toolVSAvoidreadmission prediction reliability
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The system replaces manual clinical assessment mechanisms with automated machine learning models. These computational models process patient data and generate readmission risk predictions, substituting human judgment with algorithmic analysis that can incorporate complex interactions among multiple features while providing consistent, objective predictions

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS20230019580A1Pneumonia readmission prevention
Publication Date: 2023.01.19 CERNER INNOVATION INC
  • US20230019580A1 patent drawing
  • US20230019580A1 patent drawing
  • US20230019580A1 patent drawing

AI summary

A decision support tool is provided for discharging a patient by predicting the probability of a patient's readmission with pneumonia based on information available prior to discharge. The information used to make the prediction may include labs, vitals, diagnoses, and medications from prior encounters and from the current encounter. At least some of this information may be used to compute one or more severity metrics for the patient, such as a cancer score, an epilepsy or seizure score, a pneumococcal pneumonia score, and an instability score, to be input into one or more prediction models. An ensemble of machine learning models may be applied to the patient information to generate a prediction of that patient being readmitted with pneumonia within a future time interval. Based on the prediction, one or more intervening actions may be initiated to reduce the probability of readmission.