Polarization Analysis Rectangular Wave Phase Correction

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Solution Overview

Problem

Existing polarization analysis apparatuses face challenges in accurately calculating the degree of polarization due to phase relationship inaccuracies and offset issues when using rectangular wave signals, which affect the precision of viscosity and substance analysis in fluorescence polarization immunoassays.

Innovation Solution

A polarization analysis apparatus with a controller that corrects the rectangular wave signal by calculating and applying a corrected reference voltage, ensuring the luminance change forms a sine wave, thereby improving the accuracy of polarization degree calculation through precise phase control and image sensor operation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If a rectangular wave signal is used to drive the polarization selection element, then the device complexity is reduced and operation is simplified, but the calculation accuracy of polarization degree deteriorates due to phase relationship inaccuracies and offset issues

Engineering Contradiction:
Improvecontrol signal complexityVSAvoidpolarization degree calculation accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent applies parameter changes by introducing a correction value that modifies the rectangular wave drive signal parameters. Specifically, the correction value compensates for phase relationship inaccuracies and offset issues in the rectangular wave signal, allowing the system to maintain simple rectangular wave control while achieving accurate polarization degree calculation through parameter adjustment rather than fundamental signal waveform change

Inventive Principle:
Principle #35Parameter changes

2Ease of operation

If phase relationship control is relaxed, then the ease of operation improves, but the measurement precision of polarization degree deteriorates

Engineering Contradiction:
Improvephase control requirementVSAvoidpolarization degree accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent implements feedback by calculating a correction value based on the actual phase relationship between the rectangular wave signal and the sine wave signal. This correction value is then applied to compensate for phase deviations, creating a feedback loop that maintains measurement accuracy without requiring strict manual phase control. The system automatically adjusts for phase relationship variations through this feedback mechanism

Inventive Principle:
Principle #23Feedback

3Measurement precision

If a sine wave drive signal is used, then the measurement precision of polarization degree is maintained, but the device complexity increases and productivity decreases

Engineering Contradiction:
Improvepolarization degree calculation accuracyVSAvoidmeasurement speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent substitutes the mechanical approach of using complex sine wave signals with an electronic correction approach. Instead of generating complex sine wave drive signals that require precise phase control hardware, the system uses simple rectangular wave signals enhanced by computational correction values. This substitution maintains measurement precision while improving productivity through faster, simpler signal generation and processing

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The correction of the rectangular wave signal enhances the calculation accuracy of the polarization degree, leading to improved precision in estimating liquid viscosity and substance analysis, even in cases where phase relationships are not constant.

Implementation Method 1

a light source that radiates first light causing a sample to be in an excitation state

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Implementation Method 2

a polarization selection element that outputs polarized light in a specific direction from second light radiated from the excited state sample in response to a voltage applied based on control information on a rectangular wave

Methodology Applied
Scientific EffectElectro-optic effect: Electro-Optic Effects

Data Source

PatentUS10508991B2Polarization analysis apparatus and control method of polarization analysis apparatus
Publication Date: 2019.12.17 TIANMA JAPAN LTD
  • US10508991B2 patent drawing
  • US10508991B2 patent drawing
  • US10508991B2 patent drawing

AI summary

A polarization analysis apparatus includes: a light source that radiates light to a sample; a liquid crystal panel that outputs polarized light in a specific direction from light radiated from an excited state sample; an image sensor that measures a luminance of polarized light; and a controller that controls the liquid crystal panel and the image sensor. The controller calculates a reference voltage of a rectangular wave; calculates a corrected reference voltage by correcting the reference voltage in the rectangular wave where an absolute value of the reference voltage changes in response to a phase change; applies the reference voltage and the corrected reference voltage to the liquid crystal panel; operates the image sensor in accordance with a light exposure time to measure luminance of polarized light; and calculates a degree of polarization of the sample based on results of the measurement.