Polyferric Sulfate Injection for Pathological Tissue Dehydration
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Solution Overview
Problem
Current medical treatments lack effective methods for dehydrating, atrophying, and eliminating pathological tissues, such as hemorrhoids, hemangiomas, and tumors, which often rely on invasive procedures or ineffective drugs.
Innovation Solution
A pharmaceutical composition comprising inorganic polymeric ferric salts, like polyferric sulfate, and their composites, which are traditionally used as water treatment agents, are adapted for medical use to dehydrate and atrophy pathological tissues by flocculating and eliminating them through dehydration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If traditional medical treatments are used for pathological tissues, then invasive procedures or ineffective drugs are required, but this leads to higher treatment complexity and limited effectiveness
Solution Approach 1:
The patent changes the chemical parameters of the treatment by using polyferric sulfate with specific molecular weight and composition ratios. The active ingredient is defined as containing 1-60 wt% inorganic polymeric ferric salt, with specific ratios of ferric salt to carrier, achieving effective dehydration and atrophy of pathological tissues through controlled chemical parameters rather than invasive procedures
Solution Approach 2:
The patent replaces mechanical invasive procedures (surgery, radiation, chemotherapy) with a chemical solution-based approach. The polyferric sulfate solution is injected directly into pathological tissues, using chemical flocculation and dehydration mechanisms instead of mechanical removal or radiation damage, thereby reducing treatment complexity and invasiveness
2Adaptability or versatility
If inorganic polymeric ferric salt is used as flocculant in water treatment, then high removal ratio for impurities is achieved, but its application in medical field for dehydrating pathological tissues is unexplored
Solution Approach 1:
The patent demonstrates the multi-functionality of inorganic polymeric ferric salt by transitioning it from solely water treatment application to dual applications: water treatment (flocculation, turbidity removal) and medical treatment (dehydration, atrophy of pathological tissues). The same chemical mechanism of flocculation and protein precipitation serves both purposes, expanding the adaptability and versatility of the substance
Solution Approach 2:
The patent uses polyferric sulfate as an intermediary substance that bridges water treatment technology and medical therapy. The solution acts as a mediator that delivers ferric salt to pathological tissues through injection, where it then performs the dehydration and atrophy function, serving as a transfer medium between the flocculant and the target tissue
3Reliability
If conventional flocculants are used alone for treating pathological tissues, then treatment specificity is limited, but combining multiple flocculants increases complexity
Solution Approach 1:
The patent employs composite material principles by formulating a pharmaceutical composition that combines inorganic polymeric ferric salt with organic carriers and adjuvants. The composition includes ferric salt (1-60 wt%), carrier (30-80 wt%), and optional adjuvants, creating a composite system that enhances the specificity and effectiveness of pathological tissue treatment while managing complexity through structured formulation
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively dehydrates and eliminates pathological tissues, reducing their volume significantly, promoting tissue absorption or sloughing, and is cost-effective with minimal side effects, offering rapid and significant improvements in treating vascular and topical traumas.
Implementation Method 1
When polyferric sulfate is hydrolyzed in water it will produce poly-nuclear hydroxyl complex, which has a strong absorption for colloidal particles in a variety of water body and makes the particles aggregate and flocculate through bonding, bridging, and cross-linking
Implementation Method 2
polyferric sulfate... has a strong absorption for colloidal particles in a variety of water body
Data Source
AI summary
The present invention provides a pharmaceutical composition for dehydrating, atrophying and eliminating pathological tissues comprising inorganic polymeric ferric salt and/or inorganic polymeric ferric salt composite as its active ingredients, in which the inorganic polymeric ferric salt is polyferric sulfate, and the inorganic polymeric ferric salt composite is selected from a group consisting of poly-silicate ferric salts, polyphosphate ferric salts and their analogue. A surprising medical effect can be reached by treating pathological tissues with the pharmaceutical composition of the present invention which will make the treated pathological tissues dehydrated, atrophied, and absorbed or sloughed off. The pharmaceutical composition of the present invention is cost-effective, convenient to use and has significant effects in treatment of hemorrhoids, hemangiomas, varix, hygromas, abscess, tumors, scalding and burning wounds, bleeding traumatic wounds, and/or local injuries caused by chemical agents or microorganism.