Polyhydroxy Ear Drops for Dry Inflammation

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Solution Overview

Problem

Current treatments for inflammation in the inner ear, such as those caused by asteatosis, often over-dry the ear canal, leading to irritation and increased susceptibility to infections due to the use of alcohol, hydrogen peroxide, or pH-unbalanced compositions, which can strip the ear of its natural protective waxes and oils.

Innovation Solution

A topical ear drop composition using natural anti-inflammatory, anti-irritant, and wound-healing ingredients like avenanthramide, alpha-bisabolol, Aloe, White Willow Bark extract, and liquorice root extract dissolved in a polyhydroxy solvent, providing emollient and lubrication properties to treat dry ear inflammation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If alcohol is used to clean the ear, then the ear is dried and cleaned, but the ear becomes over-dried and irritated

Engineering Contradiction:
Improvecleaning effectivenessVSAvoidirritation and over-drying
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical parameters of the cleaning solution by using natural oils and fats instead of alcohol, and by adjusting the pH to be balanced (around 7), thereby reducing irritation while maintaining cleaning effectiveness

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses a composite formulation containing multiple natural ingredients including oils, fats, and pH-balancing agents to achieve both cleaning and protective functions simultaneously, avoiding the harsh effects of single-ingredient alcohol solutions

Inventive Principle:
Principle #40Composite materials

2Reliability

If acetic acid and alcohol mixture is used to kill bacteria and eliminate yeast infections, then infections are eliminated, but the ear becomes over-dried and irritated

Engineering Contradiction:
Improveinfection eliminationVSAvoidover-drying and irritation
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the pH parameter to be balanced (around 7) instead of using highly acidic acetic acid, and replaces alcohol with natural oils and fats, thereby maintaining antimicrobial effectiveness while reducing drying and irritation effects

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses natural, biodegradable ingredients that are gentle on the ear canal skin, replacing harsh synthetic chemicals with softer natural alternatives that provide sufficient antimicrobial action without causing long-term damage

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Ease of operation

If Q-tips are used to clean the ear, then the ear is cleaned, but the protective earwax coating is stripped causing dry ear and inflammation

Engineering Contradiction:
Improvecleaning convenienceVSAvoidloss of protective earwax and dryness
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent uses natural oils and fats that replenish rather than remove earwax, providing a gentle cleaning approach that maintains the protective barrier while removing debris, unlike mechanical cotton tips that strip the coating

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The composition allows the ear's natural protective mechanisms to work by replenishing oils and fats that the ear produces naturally, rather than mechanically removing the protective layer with cotton tips

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively reduces irritation, promotes healing, and prevents infections by maintaining the ear's natural moisture balance, as demonstrated by prolonged infection-free periods in clinical examples.

Implementation Method 1

A topical ear drop composition using natural anti-inflammatory, anti-irritant, and wound-healing ingredients like avenanthramide, alpha-bisabolol, Aloe, White Willow Bark extract, and liquorice root extract dissolved in a polyhydroxy solvent

Methodology Applied
Scientific EffectDissolution: Solvation

Implementation Method 2

The composition of the present invention has emollient and lubrication properties and is topically applied as ear drops to the ear of a patient to treat asteatosis or dry ear

Methodology Applied
Scientific EffectEmollient effect: Lubrication

Data Source

PatentUS7879372B2Method and composition for treating ear inflammation caused by dry ear
Publication Date: 2011.02.01 YOSHPE NINA

AI summary

A method of treating diseases and conditions associated with dry ear comprising topically applying to the ear canal of a subject that is suffering therefrom a liquid composition comprising an anti-irritant agent, a wound healing agent; and an anti-inflammatory agent dissolved in a polyhydroxy liquid solvent.