Polymer Decolorization via Photocatalysis and Metal Scavenging

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Solution Overview

Problem

Existing methods for purifying and decolorizing polymers, particularly those containing glycolides or synthesized with reducing sugars, are inefficient, unreliable, and generate flammable solvents, with metal catalysts often being tightly bound and toxic, posing risks for parenteral administration.

Innovation Solution

A method involving the addition of a metal scavenger to form a complex with metal contaminants, followed by separation and the use of a photocatalyst like titanium dioxide exposed to UV light to remove color and separate the photocatalyst, while using a metal scavenger chelating agent to effectively remove metal catalysts like tin.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If activated charcoal is used to remove color and metal catalysts from polymer solutions, then purification effectiveness is improved, but filter clogging occurs due to fine carbon particles

Engineering Contradiction:
Improvepurification effectivenessVSAvoidfilter clogging
Core Design Contradiction:
Manufacturing precisionVSObject-generated harmful factors

Solution Approach 1:

The patent uses a porous support material as an intermediary carrier to hold the activated charcoal particles. This support structure prevents the fine carbon particles from detaching and clogging filters, while still allowing the activated charcoal to effectively adsorb color and metal catalysts from the polymer solution.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If recirculation through carbon bed is used to prevent filter clogging, then filter reliability is improved, but process complexity and time increase

Engineering Contradiction:
Improvefilter reliabilityVSAvoidprocess complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the purification function by combining the activated charcoal adsorbent with a porous support material in a single integrated filter cartridge. This eliminates the need for complex recirculation systems while maintaining filter reliability and preventing clogging.

Inventive Principle:
Principle #1Segmentation

3Productivity

If metal catalysts are tightly bound to polymer, then catalytic efficiency is improved, but biocompatibility deteriorates due to metal toxicity

Engineering Contradiction:
Improvecatalytic efficiencyVSAvoidmetal toxicity
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent extracts metal catalysts from the polymer solution using activated charcoal adsorption. The porous support material enables effective separation of the adsorbed metal catalysts from the polymer, removing the toxic metal components while preserving the polymer product.

Inventive Principle:
Principle #2Taking out (Extraction)

4Manufacturing precision

If large quantities of activated carbon are used to prevent filter clogging, then purification effectiveness is improved, but quantity of substance consumed increases

Engineering Contradiction:
Improvepurification effectivenessVSAvoidactivated carbon consumption
Core Design Contradiction:
Manufacturing precisionVSQuantity of substance

Solution Approach 1:

The patent employs a porous support material that provides a high surface area structure for holding activated charcoal particles. This porous structure increases the effectiveness of the activated carbon, allowing smaller quantities to achieve the same purification results while preventing particle detachment.

Inventive Principle:
Principle #31Porous materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method achieves high purity and safety by efficiently removing color and metal contaminants without affecting critical polymer attributes, suitable for large-scale purification of polymer solutions intended for pharmaceutical use, ensuring biocompatibility and reducing the risk of metal toxicity.

Implementation Method 1

adding a metal scavenger to the polymer composition to form a complex with a metal contaminant in the polymer composition

Methodology Applied
Scientific EffectChelation: Chemical Bonding

Implementation Method 2

adding a photocatalyst to the polymer composition; exposing the polymer composition to ultraviolet (UV) light to remove color from the polymer composition

Methodology Applied
Scientific EffectPhoto-oxidation: Photo-oxidation

Data Source

PatentEP3408305B1Purification and decolorization of polymers
Publication Date: 2024.03.06 TOLMAR INC
  • EP3408305B1 patent drawingFigure 1

AI summary

Methods according to the present invention decolorize a polymer by mixing a solution of the polymer with a photocatalyst and exposing the mixture to ultraviolet light; by way of non-limiting example, the polymer may be a star polymer and the photocatalyst may be titanium dioxide. Methods according to the present invention also utilize a metal scavenger, in some embodiments a solid-phase metal scavenger, to remove a metal catalyst from a polymer solution; by way of non-limiting example, the metal catalyst may be a tin catalyst. The decolorization methods and the catalyst removal methods of the present invention may be practiced separately, sequentially in any order, or simultaneously.