Polymer Matrix Transdermal Delivery for Animal Pain Relief
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Solution Overview
Problem
Current topical cannabinoid products for pain and stress relief in animals face challenges with bioavailability and stability due to volatility, degradation, and difficulty in achieving effective penetration through fur, leading to reduced efficacy and short duration of action.
Innovation Solution
A solid polymer matrix is used as a vehicle for transdermal delivery of THC-free cannabidiol (CBD) and other active ingredients, providing a stable and controlled release of cannabinoids directly through the skin, enhancing bioavailability and duration of effect.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If topical cannabinoid products are applied to animals, then pain and stress relief is achieved, but bioavailability is reduced due to volatility, degradation, and difficulty in penetrating fur
Solution Approach 1:
The patent changes the physical state of cannabinoid delivery from liquid (oils, creams, gels) to solid polymer matrix form. This parameter change eliminates volatility and oxidation degradation, while the solid matrix enables controlled release and improved penetration through animal fur, directly resolving the bioavailability problem while maintaining therapeutic effectiveness
Solution Approach 2:
The patent uses composite polymer materials (polyethylene, polypropylene, polyester, or polyurethane) as the delivery vehicle. These composite materials provide structural stability, control over drug release kinetics, and enhanced penetration capabilities through fur, thereby improving both bioavailability and reliability of pain and stress relief
2Reliability
If topical cannabinoid products are applied repeatedly to maintain effectiveness, then desired systemic effects are achieved, but loss of active ingredients occurs due to volatility, degradation, and washing
Solution Approach 1:
By transforming the delivery system from liquid to solid polymer matrix, the patent eliminates volatility and resistance to washing. The solid matrix physically entraps cannabinoids, preventing loss through evaporation or washing, while controlled release mechanisms ensure sustained therapeutic levels without repeated application
Solution Approach 2:
The solid polymer matrix provides continuous controlled release of cannabinoids over extended periods. This continuous action maintains therapeutic effectiveness without requiring repeated applications, thereby preventing loss of active ingredients while ensuring sustained pain and stress relief
3Ease of operation
If liquid cannabinoid formulations are used for topical application, then ease of application is achieved, but stability is reduced due to oxidation and UV degradation
Solution Approach 1:
The patent changes the physical state from liquid to solid polymer matrix, which inherently protects cannabinoids from oxidation and UV degradation. The solid matrix provides a stable environment that prevents chemical degradation while the formulation can still be easily applied to animals in various forms (collars, patches, implants)
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The polymer matrix ensures a stable and prolonged release of active ingredients, improving pain and stress relief in animals by increasing bioavailability and maintaining effectiveness over a longer period.
Implementation Method 1
offering, in use, a continuous, controlled, effective and progressive diffusion of the active ingredients on the subject to be treated
Implementation Method 2
The device according to the invention must be stable to evaporation, risk of loss in particular by leaching
Data Source
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AI summary
The invention relates to a device for topical application in the form of a polymer matrix containing at least one active ingredient from the family of cannabinoids, alone or as a mixture with other active ingredients. The invention preferably relates to the device in the form of a collar, to the use thereof for improving the well-being and the mobility of an animal to which the device is applied, and to a process for producing the device.