Biodegradable Polymer Scaffold for Prostheses
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Solution Overview
Problem
Existing technologies for tissue regeneration and drug delivery in prostheses face challenges such as the need for subsequent surgery to remove the scaffold, leakage issues, and inadequate customization to individual patient needs.
Innovation Solution
A polymer scaffold for a prosthesis composed of two outer sheets made of biodegradable synthetic polymer material and an inner sheet made of biodegradable natural polymer material, formed into a sealed pouch with customizable dimensions and drug delivery control, using electrospinning to create a fine network structure with controlled porosity and density.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a tube-shaped instrument is used to fill liquid at the surgical site, then the surgical site can be protected and rehabilitation pain can be reduced, but the tube must be prevented from melting inside the body requiring separate removal surgery
Solution Approach 1:
The prosthesis is divided into multiple layers with different materials: an inner sheet made of biodegradable natural polymer material that can be absorbed by the body, and outer sheets made of non-biodegradable synthetic polymer material that provides structural support. This segmentation allows the protective function to be maintained while eliminating the need for removal surgery.
Solution Approach 2:
The invention changes the material parameters of the prosthesis by using biodegradable natural polymer materials with controlled degradation rates. The inner sheet is designed to degrade at a specific rate that matches tissue regeneration, allowing the prosthesis to be temporarily protective without requiring permanent implantation or removal.
2Loss of time
If biodegradable polymer material is used for the prosthesis, then subsequent removal surgery can be eliminated, but the strength and stability of the prosthesis may be insufficient
Solution Approach 1:
The prosthesis uses a composite structure combining biodegradable natural polymer materials (for the inner sheet) with non-biodegradable synthetic polymer materials (for the outer sheets). This composite approach allows the inner sheet to provide biocompatibility and gradual degradation while the outer sheets provide structural strength and stability, resolving the contradiction between biodegradability and strength.
3Adaptability or versatility
If the scaffold is customized to fit specific patient needs, then treatment effectiveness can be improved, but manufacturing complexity and costs increase
Solution Approach 1:
The invention prepares standardized prosthesis components (inner sheet and outer sheets) in advance with different material properties and structural characteristics. These pre-fabricated components can be selectively combined and customized for different patients based on their specific needs, reducing manufacturing complexity while maintaining adaptability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The scaffold can be customized to fit specific patient needs, reducing the need for subsequent surgery, controlling drug delivery rates, and providing sustained support to the affected area during tissue regeneration.
Implementation Method 1
the synthetic polymer matrix may be preferably formed into a fine network structure through amorphous stacking of synthetic polymer fibers that are injected by applying a high voltage to a piston nozzle
Data Source
AI summary
The present invention is to provide a polymer scaffold for a prosthesis includes two outer sheets formed into a certain size and shape and made of a biodegradable synthetic polymer material, and an inner sheet disposed between the two outer sheets and made of a biodegradable natural polymer material, wherein the two outer sheets are formed in the form of a single sealed pouch by joining the edges of the two outer sheets together, and the outer sheets are formed by cutting a portion of a synthetic polymer matrix made of the biodegradable synthetic polymer material and having a larger area and thickness than the outer sheets, and the inner sheet is formed by cutting a portion of a natural polymer matrix made of the biodegradable natural polymer material and having a larger area and thickness than the inner sheet.


