Polymeric Binding System for N-Halamine Coatings

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Solution Overview

Problem

Current antimicrobial and deodorizing technologies are insufficient in effectively inactivating microorganisms and reducing odors on environmental surfaces, leading to the transmission of infectious diseases, particularly in healthcare settings, due to the persistence of pathogens on surfaces and the limited durability and effectiveness of existing antimicrobial coatings.

Innovation Solution

Development of multifunctional compositions with halogen-stabilizing agents and novel binding systems to immobilize N-halamine compounds on various surfaces, providing potent antimicrobial, deodorizing, and enzyme-inhibiting functions, reducing chlorine odor and gas phase corrosiveness, and enhancing the stability and durability of antimicrobial coatings.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If N-halamine compounds are applied to surfaces for antimicrobial function, then microorganism inactivation effectiveness is improved, but chlorine odor and gas phase corrosiveness increase

Engineering Contradiction:
Improvemicroorganism inactivation effectivenessVSAvoidchlorine odor and gas phase corrosiveness
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent uses polymeric binders as intermediary substances to immobilize N-halamine compounds on surfaces. These polymers act as carriers that hold the active antimicrobial agents in place, reducing their volatility and gas phase release while maintaining their biocidal effectiveness against microorganisms.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention creates composite material systems combining N-halamine compounds with polymeric binders and stabilizing agents. This composite approach allows the beneficial antimicrobial properties of N-halamines to be retained while the polymer matrix suppresses chlorine odor and gas phase corrosiveness through physical containment and chemical stabilization.

Inventive Principle:
Principle #40Composite materials

2Reliability

If existing antimicrobial coatings are applied to surfaces, then some level of microbial protection is provided, but durability and persistence of the coating are insufficient

Engineering Contradiction:
Improvemicrobial protection levelVSAvoidcoating durability and persistence
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent applies preliminary stabilization measures by incorporating stabilizing agents and using polymeric binders before the N-halamine compounds are deployed for antimicrobial action. This preliminary bonding and stabilization ensures the coating persists longer on surfaces while maintaining its microbial protection capabilities.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The polymeric binder system provides continuous attachment of N-halamine compounds to surfaces, ensuring sustained release and prolonged antimicrobial activity. The coating maintains its protective function over extended periods through the continuous presence of the polymer matrix that holds the active ingredients in place.

Inventive Principle:
Principle #20Continuity of useful action

3Ease of operation

If conventional binding methods are used to apply antimicrobial agents, then application simplicity is maintained, but the stability and durability of the coating are limited

Engineering Contradiction:
Improveapplication simplicityVSAvoidcoating stability and durability
Core Design Contradiction:
Ease of operationVSStability of the object's composition

Solution Approach 1:

The patent changes the binding parameters by using polymeric binders with specific molecular weights, functional groups, and adhesive properties. These parameter optimizations in the binder system enhance coating stability and durability while maintaining relatively simple application procedures through dip-coating, spray-coating, or roll-coating methods.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The proposed solution effectively inactivates a broad spectrum of microorganisms, degrades malodorous compounds, and inhibits enzyme activity, providing persistent antimicrobial and deodorizing protection on surfaces for an extended period, thereby reducing the risk of infectious disease transmission and improving surface hygiene.

Implementation Method 1

The N-halamines can be immobilized onto targeting subjects via polymeric binder with physical and/or chemical bindings with synergism. The interactions include but are not limited to van der Waals interaction, complex combination, ionic interaction, hydrogen bonds, crosslinking, free radical interaction, etc.

Methodology Applied
Scientific EffectPhysical binding: Adsorption

Implementation Method 2

The N-halamines can be immobilized onto targeting subjects via polymeric binder with physical and/or chemical bindings with synergism. The interactions include but are not limited to van der Waals interaction, complex combination, ionic interaction, hydrogen bonds, crosslinking, free radical interaction, etc.

Methodology Applied
Scientific EffectChemical binding: Chemical Bonding

Implementation Method 3

the discovered halogen stabilizing compositions can provide reduction of chlorine odor emanating from N-halamine-based antimicrobial and deodorizing subjects. Without limiting the scope of the invention, the discovered halogen stabilizing compositions can provide reduction of corrosion caused by halogens from N-halamines.

Methodology Applied
Scientific EffectHalogen stabilization: Oxidation

Data Source

PatentUS10721907B2Antimicrobial compositions and methods with novel polymeric binding system
Publication Date: 2020.07.28 OXISCIENCE WA LLC
  • US10721907B2 patent drawing
  • US10721907B2 patent drawing
  • US10721907B2 patent drawing

AI summary

The present invention includes multifunctional compositions, methods and binding systems to provide disinfecting and deodorizing coatings for hard and soft surfaces, inorganic and organic solid surfaces and particulate media and other related substrates, including human and animal skin and skin lesions; to provide neutralizing functions for malodors generated by both human, animal and industrial fluids and solid wastes; and to provide neutralizing and degrading functions for nuisance and noxious chemicals. The present invention provides compositions and methods for producing disinfecting, oxidizing and enzyme-inhibiting fluids enabling preparation of durable, stable biocidal and deodorizing coatings and media which can be widely used for biological agent control, prevention and elimination of odors, and degradation of noxious agents susceptible to chemical oxidation, and which take forms that are inoffensive to users and offer high convenience.