3D Polymeric Implants with Segmented Porous and Organized Core

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Solution Overview

Problem

Three-dimensional medical implants with high porosity face challenges in achieving adequate load-bearing capacity without rigidity, controlling mechanical properties, and maintaining pore homogeneity, especially in soft tissue applications, where unorganized structures like foams struggle to withstand compressive forces and have variable material properties.

Innovation Solution

A three-dimensional resorbable polymeric medical implant with a porous surface component and a load-bearing, volume-creating component featuring an organized, formed two-dimensional structure, which can be sandwiched between multiple porous components, allowing for controlled bending stiffness and compressive strength, enabling predictable mechanical properties and adaptability to tissue structures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If high porosity (>70%) is used in three-dimensional implants to enable tissue ingrowth, then tissue integration is improved, but load-bearing capacity and compressive strength deteriorate

Engineering Contradiction:
Improvetissue integrationVSAvoidcompressive strength
Core Design Contradiction:
ReliabilityVSStrength

Solution Approach 1:

The implant is divided into multiple layers with different functions: outer porous layers for tissue integration and an inner organized core layer for mechanical strength. This segmentation allows each layer to optimize its specific function without compromising the other.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The implant combines different structural configurations within a single device - unorganized porous structures in outer layers for biocompatibility and tissue ingrowth, and an organized uniaxial or biaxial structure in the core for enhanced compressive strength and load-bearing capacity.

Inventive Principle:
Principle #40Composite materials

2Strength

If stiff materials are used to increase load-bearing capacity, then compressive strength is improved, but adaptability to soft tissue structures deteriorates

Engineering Contradiction:
Improvecompressive strengthVSAvoidadaptability to tissue
Core Design Contradiction:
StrengthVSAdaptability or versatility

Solution Approach 1:

Different regions of the implant have different mechanical properties tailored to their specific functions. The outer porous layers are more compliant for tissue adaptation, while the inner organized core provides stiffer load-bearing support where needed.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The implant's organized core structure can dynamically adjust to compression forces through its uniaxial or biaxial configuration, allowing the material to exhibit varying stiffness characteristics depending on the direction and magnitude of applied loads.

Inventive Principle:
Principle #15Dynamics

3Reliability

If unorganized porous structures like foams are used to achieve high porosity, then tissue ingrowth is facilitated, but pore homogeneity and mechanical property control deteriorate

Engineering Contradiction:
Improvetissue ingrowthVSAvoidpore homogeneity
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The implant structure is segmented into outer unorganized porous layers that facilitate tissue ingrowth and an inner organized core with controlled pore architecture. This segmentation allows independent optimization of pore homogeneity in the core while maintaining tissue-friendly porosity in the outer layers.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentEP2762172B1Three-Dimensional Polymeric Medical Implants
Publication Date: 2015.06.17 NOVUS SCI
  • EP2762172B1 patent drawingFigure 1~3
  • EP2762172B1 patent drawingFigure 4~8
  • EP2762172B1 patent drawingFigure 9~11

AI summary

The invention relates to a three-dimensional medical implant, comprising a substantially two-dimensional, porous component, and a load-bearing and volume-creating component, which is connected to the substantially two-dimensional, porous component; wherein the load-bearing and volume-creating component comprises an organized structure, which is a formed two-dimensional structure.