In Situ Polymerizable Wound Seal for Trauma Management
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Solution Overview
Problem
Current wound treatment options for non-medical professionals are inadequate in effectively stopping severe bleeding, stabilizing trauma sites, and remaining in place for extended periods without retraumatizing the patient, especially for serious injuries like stab wounds, lacerations, or amputations.
Innovation Solution
A polymerizable composition that forms a seal in situ, which is elastic or semi-elastic, allowing for movement and stretching, and can be removed intact without causing further injury, incorporating additional ingredients like anesthetics, antiseptics, and adhesion promoters, and can cure faster in the presence of blood, providing a secure seal for extended periods.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Duration of action of moving object
If conventional wound treatment materials (gauze, cloth) are applied to stop bleeding, then bleeding can be temporarily controlled, but the materials require constant direct pressure and cannot remain in place for extended periods without third-party intervention
Solution Approach 1:
The polymerizable composition is designed to self-adhere to the wound site and self-maintain the seal without requiring constant external pressure or monitoring. The material autonomously remains in place for extended periods, eliminating the need for third-party intervention to maintain pressure on the wound.
Solution Approach 2:
The composition is applied in a state that enables it to progressively form a durable seal before complete setting occurs. The preliminary application allows the material to adapt to the wound geometry and establish initial adhesion, which then matures into a long-lasting seal that persists without further intervention.
2Ease of repair
If removable wound materials are applied to seal a wound, then the wound can be temporarily protected, but removal often causes further traumatic injury especially after prolonged contact
Solution Approach 1:
The composition undergoes controlled parameter changes during its service life. It transitions from an initially compliant state that adapts to the wound to a stabilized state that maintains the seal, and finally to a removable state where adhesion is reduced enough to allow painless removal. This temporal variation in adhesion parameters enables both effective sealing and easy removal without trauma.
3Duration of action of moving object
If a seal material is applied to stop bleeding and remain for extended periods, then wound protection is improved, but the material must withstand movement and stretching without dislodging
Solution Approach 1:
The seal material exhibits dynamic mechanical properties that adapt to physiological conditions. It possesses elastic and semi-elastic characteristics that allow it to stretch and deform with body movements while maintaining continuous adhesion to the wound site. The material's viscoelastic behavior enables it to absorb mechanical stresses without dislodging, thereby maintaining the seal during patient movement.
4Ease of operation
If polymerizable composition is used to form a seal, then the seal can be elastic and removable without injury, but the composition must cure fast enough to provide immediate protection
Solution Approach 1:
The polymerizable composition undergoes controlled parameter changes during curing. It transitions from a liquid or semi-liquid state that can be easily applied and adapted to the wound, through a gelation phase that provides initial structural integrity, to a final cured state that maintains elasticity and removability. This staged parameter change enables both rapid protection and safe removal.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The polymerizable composition effectively stops bleeding, stabilizes trauma sites, remains adhered for several hours or days, and can be removed without re-injury, making it suitable for temporary or primary wound treatment until medical attention is available.
Implementation Method 1
a polymerizable composition that forms a seal in situ
Implementation Method 2
which is elastic or semi-elastic, allowing for movement and stretching
Data Source
AI summary
The inventive subject matter provides compositions and methods for transiently or permanently treating or managing an injury. Contemplated compositions are polymerizable in situ over short time periods, even in the presence of blood, without undue exothermic heat. Contemplated compositions may further comprise an anesthetic, an antiseptic, an adhesion promoter, and/or a vasoconstrictor.