Topical Compositions Using Polyolprepolymers and Cannabinoids

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Solution Overview

Problem

Current treatments for skin disorders such as dermatitis and skin aging lack long-term efficacy, with existing moisturizers and steroid creams providing only temporary relief and no known cure for dermatitis.

Innovation Solution

Topical compositions combining cannabinoids, polyolprepolymers, stem cell extracts, and BV-OSC (tetrahexyldecy ascorbate) are used to treat skin disorders, enhancing skin health through modulation of cannabinoid receptors and anti-inflammatory effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If moisturizers and steroid creams are used to treat skin disorders, then temporary relief from symptoms is achieved, but long-term efficacy is not obtained

Engineering Contradiction:

Improvelong-term efficacyVSAvoidduration of relief

Core Design Contradiction:

ReliabilityVSDuration of action of moving object

Solution Approach 1:

The patent combines multiple active ingredients (cannabinoids, polyolprepolymers, stem cell extracts, and BV-OSC) into a single topical composition. This composite approach synergistically addresses inflammation, moisture retention, and skin regeneration, providing both immediate symptom relief and long-term therapeutic effects, thereby resolving the contradiction between temporary relief and long-term efficacy.

Inventive Principle:

Principle #40Composite materials

Solution Approach 2:

The patent utilizes polyolprepolymers that undergo phase transition from liquid to gel upon contact with skin moisture. This parameter change enables the composition to transform from a spreadable liquid to a stable gel film on the skin, providing sustained release of active ingredients and extending the duration of action from temporary to long-term therapeutic effect.

Inventive Principle:

Principle #35Parameter changes

2Reliability

If topical compositions are applied to treat skin disorders, then skin improvement effects are achieved, but irritation may occur

Engineering Contradiction:

Improveskin improvement effectsVSAvoidirritation

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent employs polyolprepolymers as intermediary carriers that gently deliver cannabinoids and stem cell extracts to the skin. These prepolymers form a protective gel matrix that controls the release of active ingredients, reducing direct irritation while maintaining therapeutic efficacy. The gradual release mechanism mediates between the need for effective treatment and the avoidance of irritation.

Inventive Principle:

Principle #24Intermediary (Mediator)

3Reliability

If existing treatments are used for skin aging, then temporary smoothing of wrinkles is achieved, but permanent prevention of skin aging is not obtained

Engineering Contradiction:

Improvepermanent prevention of skin agingVSAvoidduration of wrinkle smoothing

Core Design Contradiction:

ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent incorporates stem cell extracts that actively stimulate skin regeneration and collagen production before significant aging damage occurs. This preliminary regenerative action addresses the root causes of skin aging (cellular degradation and collagen loss) rather than merely masking symptoms, providing long-term prevention and permanent improvement rather than temporary smoothing.

Inventive Principle:

Principle #10Preliminary action

Data Source

PatentUS10864189B2Topical compositions comprising polyolprepolymers, stem cell, and cannabinoids for skin care

Publication Date: 2020.12.15 BOROK JENNA

AI summary

The present invention relates to compositions and methods for the prevention and treatment of skin disorders. In particular, the application describes topical compositions and methods of treatments comprising the combined use of one or more cannabinoids, or use of an ingredient that works on the endocannabinoid system, such as but not limited to, Palmitoylethanolamide (PEA), polyolprepolymers and stem cell extract.